Core Insights - ADC Therapeutics announced promising results from the LOTIS-7 Phase 1b clinical trial, showing an overall response rate (ORR) of 95.5% and a complete response (CR) rate of 90.9% among 22 evaluable patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL) [1][4] - The combination of ZYNLONTA and glofitamab demonstrated a manageable safety profile, with adverse events consistent with known profiles of the individual agents [2][4] - Updated data will be presented at the European Hematology Association 2025 Congress (EHA2025) and the International Conference on Malignant Lymphoma (ICML) [1][5] Efficacy and Safety Data - In the efficacy evaluable population, the ORR was 95.5% (21 out of 22 patients), and the CR rate was 90.9% (20 out of 22 patients) [4] - Among 31 patients treated, the most common Grade ≥3 treatment-emergent adverse event (TEAE) was neutropenia at 32.3% [4] - Other notable Grade 3/4 TEAEs included generalized edema, pericardial effusion, photosensitivity reaction, rash, sepsis, and pneumonia, each at 3.2% [4] Presentation Details - The LOTIS-7 data will be presented in a poster session at EHA2025 on June 14, 2025, with the presenting author being Juan Pablo Alderuccio, MD [3][5] - An oral encore presentation will take place at ICML on June 20, 2025, also featuring Juan Pablo Alderuccio as the presenting author [5] Study Overview - LOTIS-7 is a Phase 1b global multicenter study evaluating ZYNLONTA in combination with various agents, including glofitamab, in patients with relapsed or refractory B-cell non-Hodgkin lymphoma [6] - The study includes a dose escalation phase and a dose expansion phase, with primary endpoints focusing on safety and tolerability [6] About ZYNLONTA - ZYNLONTA is a CD19-directed antibody drug conjugate (ADC) approved for treating adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy [9][12] - The drug works by binding to CD19-expressing cells and delivering a potent payload that leads to tumor cell death [8]

Core Viewpoint - Five publicly traded real estate investment trusts (REITs) in the US announced increases to their regular dividend payments in April, indicating a positive trend in the sector [2] Group 1: Dividend Increases - Tanger Inc. (SKT) declared the largest percentage increase in quarterly dividend among the five REITs [2]

Group 1 - The concept of achieving financial independence or retirement often requires substantial capital accumulation over many years [1] - Roberts Berzins has over a decade of experience in financial management, focusing on corporate financial strategies and large-scale financings [1] - Berzins has contributed to the institutionalization of the REIT framework in Latvia to enhance liquidity in pan-Baltic capital markets [1] Group 2 - His policy-level work includes developing national SOE financing guidelines and frameworks to channel private capital into affordable housing [1] - Berzins holds a CFA Charter and an ESG investing certificate, and has interned at the Chicago Board of Trade [1] - He is actively involved in thought-leadership activities aimed at supporting the development of pan-Baltic capital markets [1]

Group 1 - Agree Realty Corp. (ADC) recently announced earnings that exceeded both FFO estimates and revenue [1] - ADC has demonstrated solid total return performance compared to its peers [1] Group 2 - The company is focused on providing high-quality and reliable dividend growth ideas for investors [1] - Investments are aimed at leaders within their industry to ensure stability and long-term wealth creation [1]

Core Insights - The article estimates the investment spread generated by a selected group of investment-grade net-lease REITs in Q1 2025 and ranks them accordingly [1] Group 1: Investment Analysis - The REITs discussed have all declared their Q1 results, indicating a focus on recent performance metrics [1] - The analysis is sector agnostic, allowing for a broad evaluation of various companies as long as their business models are understood [1] Group 2: Personal Background of the Analyst - The analyst has a background in finance, having earned a CFA charter and CIPM certificate, which adds credibility to the analysis [1] - The analyst's experience includes assisting firms in complying with Global Investment Performance Standards (GIPS), highlighting a strong foundation in investment performance evaluation [1]

Core Insights - ADC Therapeutics SA is a global leader in antibody drug conjugates (ADCs) and will host a conference call on May 14, 2025, to report Q1 2025 financial results and operational updates [1][2][3] Company Overview - ADC Therapeutics is advancing proprietary ADC technology aimed at transforming treatment for patients with hematologic malignancies and solid tumors [3] - The company is based in Lausanne, Switzerland, with operations in London and New Jersey [5] Product Development - ADC Therapeutics' CD19-directed ADC ZYNLONTA (loncastuximab tesirine-lpyl) has received accelerated approval from the FDA and conditional approval from the European Commission for treating relapsed or refractory diffuse large B-cell lymphoma after two or more lines of systemic therapy [4] - ZYNLONTA is also being developed in combination with other agents and in earlier lines of therapy, alongside multiple ADCs in ongoing clinical and preclinical development [4]

Core Themes - Economic uncertainty is the predominant theme of 2025, characterized by volatility, turbulence, and change [1] Government Proposals - The new presidential administration has introduced proposals aimed at addressing the current economic challenges [1]

Core Insights - Mr. Mavroudis is a professional portfolio manager with a focus on risk management and in-depth financial market analysis [1] - He has successfully navigated major crises, including the COVID-19 pandemic and the PSI [1] - Mr. Mavroudis is the CEO of FAST FINANCE Investment Services, a registered Greek company [1] Company Profile - FAST FINANCE Investment Services is registered with the Hellenic Capital Market Commission [1] - The company specializes in managing institutional and private portfolios globally across various financial instruments [1] Professional Background - Mr. Mavroudis holds multiple degrees, including an MSc in Financial and Banking Management, an LLM in Law, and a BSc in Economics, graduating as valedictorian [1] - He is certified in various financial disciplines, including portfolio management and derivatives [1] - He has published three books on investments and contributes articles to reputable financial media [1] Engagement and Community - By writing on Seeking Alpha, the company aims to engage with a community of investors and market enthusiasts [1] - The goal is to foster mutual growth and knowledge sharing within the investment community [1]

Core Viewpoint - Investing in monthly dividend stocks, particularly real estate investment trusts (REITs), provides a reliable source of passive income, making them attractive options for investors seeking regular cash flow [3][12]. Group 1: Monthly Dividend Stocks - Several REITs, including Agree Realty, EPR Properties, and Stag Industrial, offer monthly dividend payments, making them suitable for investors looking for consistent income [3][12]. - Agree Realty has a dividend yield of approximately 4%, significantly higher than the S&P 500's yield of less than 1.5% [4]. - EPR Properties boasts a higher dividend yield of over 7%, focusing on experiential properties like movie theaters and attractions [7]. Group 2: Financial Performance and Stability - Agree Realty maintains a low dividend payout ratio of 72% of its adjusted funds from operations (FFO), allowing for cash retention to invest in additional properties [6]. - EPR Properties expects its payout ratio to be between 69% and 72% of its adjusted FFO, providing a cushion for new investments while covering high-yield payouts [8]. - Stag Industrial has a 74% dividend payout ratio, generating about $95 million in annual free cash flow after dividends, which supports new investments [10]. Group 3: Growth Potential - Agree Realty has demonstrated a 5.5% compound annual dividend growth over the past decade, supported by a stable income from its retail property portfolio [6]. - EPR Properties anticipates annual FFO per share growth of 3% to 4%, aligning with its investment capacity of $200 million to $300 million each year [8]. - Stag Industrial has consistently increased its dividend since going public in 2011, driven by rental increases and value-enhancing acquisitions [11]. Group 4: Investment Strategy - The REITs mentioned are characterized by their ability to generate sufficient cash flow to cover dividends while also investing in portfolio expansion, which contributes to rental income growth [12]. - Agree Realty focuses on single-tenant properties with strong retailers, while Stag Industrial targets industrial properties with potential for higher returns through lease escalations and expansions [5][11].

Group 1 - The article highlights that REIT (VNQ) share prices have significantly declined despite consistent growth in cash flows and dividends, leading to decade-low valuations for REITs [2] - The investment group High Yield Landlord, led by Jussi Askola, provides real-time insights into REIT investments, including multiple portfolios and direct access to analysts [3] - The company invests substantial resources, over $100,000 annually, into researching profitable real estate strategies to benefit its members [1]