Financial Performance - The company reported a net loss of 3,435,881fortheninemonthsendedSeptember30,2024,comparedtoalossof4,857,289 for the same period in 2023, representing a 29.2% improvement[6] - Basic and diluted loss per common share improved to (1.25)fortheninemonthsendedSeptember30,2024,comparedto(2.46) for the same period in 2023[6] - For the nine months ended September 30, 2024, XORTX reported a net loss of 3,435,881,adecreaseof29.24,857,289 for the same period in 2023[10] - Cash provided by operating activities for the nine months ended September 30, 2024, was (2,792,240),animprovementfrom(5,285,098) in 2023, indicating a 47.1% reduction in cash outflow[10] - Management compensation for the nine months ended September 30, 2024, totaled 612,749,adecreasefrom753,401 in the same period of 2023[78] Assets and Liabilities - Total current assets decreased to 2,410,394asofSeptember30,2024,down40.84,068,783 on December 31, 2023[3] - Shareholders' equity decreased to 2,133,580asofSeptember30,2024,down54.14,642,026 on December 31, 2023[3] - The company’s cash balance was 2,300,747asofSeptember30,2024,adecreaseof33.33,447,665 on December 31, 2023[3] - Total liabilities increased to 1,716,751asofSeptember30,2024,up107.5825,938 on December 31, 2023[3] - The total accounts payable and accrued liabilities increased to 326,283asofSeptember30,2024,comparedto283,428 at December 31, 2023[42] Research and Development - Research and development expenses for the nine months ended September 30, 2024, were 176,067,adecreaseof92.32,284,583 in the same period of 2023[6] - The company has not capitalized any development costs as of September 30, 2024, indicating a focus on maintaining liquidity while pursuing R&D[27] - XORTX is focused on developing therapies for progressive kidney disease, with ongoing clinical studies and potential future product launches[13] - The company plans to raise additional capital to finance its research and development activities and clinical studies, emphasizing the need for future funding[14] Capital and Financing - The company issued 899,717 shares pursuant to a private placement, raising 1,032,549[8]−Thecompanyraised2,000,549 from the issuance of equity instruments during the nine months ended September 30, 2024, compared to no such proceeds in the same period of 2023[10] - The company closed a registered direct offering on October 18, 2024, raising aggregate gross proceeds of 1,500,000throughthesaleof320,000commonshareunitsat1.85 each and 490,810 pre-funded warrant units at 1.8499each[87]−Thecompanyintendstousethenetproceedsfromtherecentofferingforworkingcapitalandgeneralcorporatepurposes[87]StockandEquity−Theweightedaveragenumberofcommonsharesoutstandingincreasedto2,903,565asofSeptember30,2024,comparedto2,746,043forthesameperiodin2023[6]−Thecompanyissued2,903,565commonsharesasofSeptember30,2024,anincreasefrom1,998,848sharesatDecember31,2023[45]−Thecompanyhasatotalof2,019,927outstandingwarrantsasofSeptember30,2024,withaweightedaverageexercisepriceof4.26[54][56] - The company recorded share-based payments of 15,857forthethreemonthsand113,022 for the nine months ended September 30, 2024, compared to 21,850and92,169 in the same periods of 2023, respectively[62] Obligations and Commitments - The company has a total lease obligation of 61,468asofSeptember30,2024,whichincludesa96,998 addition due to an office lease extension[43][44] - The company has committed payments totaling 173,000forclinicaltrialsandotherbusinessactivities,downfrom446,000 as of December 31, 2023[85] - The company has milestone payments of 500,000uponFDAapprovaland100,000 for each additional jurisdiction's regulatory approval for licensed products[38] Financial Instruments and Valuation - The fair values of the company's financial instruments approximate their carrying values due to their short-term nature as of September 30, 2024[80] - The balance of derivative warrant liabilities as of September 30, 2024, is 1,329,000,reflectingafairvalueadjustmentof(164,756) during the period[70] - The carrying value of right-of-use assets increased to 47,018asofSeptember30,2024,from10,913 at December 31, 2023[40] Risk Management - The company has not made any changes to its risk management policies since December 31, 2023, and continues to monitor various financial risks[80] - The company has no external capital requirements imposed by regulatory agencies[82] - The company has not reported any changes in its capital management strategy during the nine months ended September 30, 2024[82]