Sales Performance - Fourth-quarter 2024 total net sales were 667.5million,adecreaseof2.0681.2 million in Q4 2023[4] - Life Science segment net sales for Q4 2024 were 275.0million,adeclineof5.5392.5 million, an increase of 0.9% compared to the same period in 2023, driven by demand for quality control and blood typing products[6] - Full-year 2024 net sales decreased 3.9% to 2,566.5millioncomparedto2,671.2 million in 2023[12] - Full-year 2024 reported net sales for the Life Science segment were 1,028.1million,adecreaseof12.61,537.9 million, an increase of 3.7% compared to the prior year[13] Financial Results - The company experienced a net loss of 715.8millioninQ42024,comparedtoanetincomeof349.7 million in Q4 2023, resulting in a basic loss per share of 25.57[37]−Forthefullyear2024,Bio−Rad′srevenuestotaled2.566 billion, down from 2.671billionin2023,markingadeclineof3.9291.1 million, or 10.31pershare,comparedto345.2 million, or 11.78persharein2023[18]−GAAPnetincomefortheperiodwas(715.8) million, a decrease of 107.2% compared to the previous year[48] - The company reported a significant loss of (1,844.2)millioninGAAPnetincomefortheyear,adecreaseof71.9342.0 million, representing 51.2% of revenue, compared to 366.3millionand53.81,411.6 million, or 55.0% of revenue, up from 1,448.3millionand54.258.4 million, or 8.7% of revenue, down from 95.3millionand14.0331.3 million, or 12.9% of revenue, compared to 378.9millionand14.279.6 million, compared to 63.9millioninQ42023[46]−Non−GAAPresearchanddevelopmentexpensefortheyearendedDecember31,2024,was281.8 million, up from 254.8millioninthepreviousyear[46]−GAAPselling,generalandadministrativeexpenseforQ42024was204.0 million, slightly down from 207.1millioninQ42023[45]−Non−GAAPselling,generalandadministrativeexpensefortheyearendedDecember31,2024,was798.5 million, compared to 814.6millioninthepreviousyear[45]FutureOutlook−Forfull−year2025,thecompanyexpectsnon−GAAP,currency−neutralrevenuegrowthofapproximately1.5488.1 million as of December 31, 2024, compared to 403.8millionattheendof2023[40]−Thecompanyreportedanetcashprovidedbyoperatingactivitiesof455.2 million for the year ended December 31, 2024, compared to 374.9millionin2023[42]−Bio−Rad′stotalassetsdecreasedto9.364 billion in 2024 from 12.299billionin2023,adeclineof23.614.7 million in the current period, compared to 2.1millioninthepreviousyear[48]−Forecastednon−GAAPoperatingmarginfor2025excludes87basispointsrelatedtoamortizationofpurchasedintangibles[51]SharePerformance−Thecompanyreportedadilutednon−GAAPincomepershareof2.90, compared to 3.10inthepreviousyear[48]−Theweightedaveragesharesusedinthenon−GAAPdilutedincomepersharecalculationwere28,025million[48]OtherFinancialMetrics−AdjustedEBITDAforthecurrentperiodwas126.1 million, reflecting an 18.9% margin, compared to 136.8millionanda20.1908.9 million for Q4 2024, compared to a profit of 428.4millioninQ42023[46]−Thecompanyexperiencedgainsfromchangesinthefairmarketvalueofequitysecuritiesandloanreceivablesamountingto976.5 million[48]