Financial Performance - Total revenues for 2024 reached 388.5million,anincreaseof9.8354.0 million in 2023[371]. - Product revenues increased to 290.2million,up11.1261.2 million in 2023[371]. - Operating income for 2024 was 38.9million,significantlyhigherthan5.7 million in 2023[371]. - Net loss decreased to 13.4millionin2024from30.7 million in 2023, reflecting a reduction of 56.3%[371]. - Basic loss per share improved to (0.32)from(0.75) in 2023[371]. - Net loss for the year ended December 31, 2024, was 13,359million,adecreasefromanetlossof30,690 million in 2023[373]. - Net cash flows provided by operating activities increased to 22,236millionin2024from18,825 million in 2023[373]. - Total current assets increased to 290.1millionin2024,upfrom280.7 million in 2023[367]. - Total liabilities rose slightly to 512.9millionin2024from510.6 million in 2023[369]. - Cash and cash equivalents decreased to 53.5millionin2024from58.9 million in 2023[367]. Employee Relations and Workforce - The company had approximately 1,600 employees as of December 31, 2024, with a focus on attracting and retaining qualified personnel in a competitive market[146]. - The company has never experienced a work stoppage or interruption due to labor disputes, indicating good relations with employees worldwide[146]. - The company has programs in place to enhance compensation and benefits to attract and retain talent in the medical device and tissue processing industries[148]. - The company emphasizes a strong and collaborative culture, with core values focused on collaboration, results-driven performance, and customer focus[149]. Internal Controls and Compliance - The company maintains effective internal control over financial reporting as of December 31, 2024, based on the COSO criteria[359]. - The company’s independent auditor, Ernst & Young, LLP, issued an unqualified opinion on the effectiveness of internal controls over financial reporting as of December 31, 2024[347]. Risks and Sensitivities - The company’s operations are subject to risks from interest rate fluctuations and foreign currency exchange rate changes, which could significantly impact financial results[332][334]. - A hypothetical increase of one percentage point in interest rates on the company's variable rate debt portfolio would decrease pre-tax operating results by an estimated 2.0millionoveratwelve−monthperiod[333].−Ahypothetical108.0 million over a twelve-month period[335]. Capital Expenditures and Investments - Capital expenditures for 2024 were 11,188million,upfrom9,752 million in 2023[373]. - The company completed the acquisition of Ascyrus Medical LLC to enhance the company's product offerings in the treatment of acute Type A aortic dissections[440]. - The total potential purchase consideration for the Ascyrus acquisition is up to 200.0million,includingcashpaymentsandstockissuanceuponachievingspecificmilestones[441].RevenueandMarketPerformance−NorthAmericagenerated197.9 million in revenue for 2024, up from 187.6millionin2023,representingagrowthof7.2131.5 million in 2024 from 114.8millionin2023,reflectingagrowthof14.616.2 million[508]. - The company did not authorize any grants of stock options during 2024, while 110,000 shares were granted in 2023[515]. Tax and Deferred Assets - Total deferred tax assets were 41.87millionasofDecember31,2024,downfrom43.14 million in 2023, with a net deferred tax liability of 19.12million[470].−Thecompanymaintainedavaluationallowanceagainstdeferredtaxassetsof32.61 million as of December 31, 2024, compared to 32.86millionin2023[470].−AsofDecember31,2024,theuncertaintaxliabilitywas5.1 million, with 4.0millionexpectedtoaffectthetaxrateifrecognized[475].DebtandFinancing−ThetotalprincipaldebtasofDecember31,2024,was320.2 million, with total debt amounting to 314.3millionafteraccountingforunamortizeddebtissuancecosts[480].−Thecompanyenteredintoacreditagreementfor350.0 million, including a 190.0millionsecuredtermloanfacilityanda60.0 million revolving credit facility[483]. - The stated interest rate for the Term Loan Facility was 11.09% as of December 31, 2024, with an effective interest rate of 11.86%[489]. - The company is in compliance with its debt covenants, which require a total net leverage ratio not greater than 6.25x for certain periods[487].