Revenue Growth - BRIUMVI U.S. net product revenue reached 103.6millioninQ42024and310 million for the full year, representing approximately 250% year-over-year growth[5] - The company targets approximately 540millionintotalglobalrevenuefor2025,includinganestimated525 million from BRIUMVI U.S. net product revenue[5] - TG Therapeutics reported total revenue of 108.185millionforQ42024,asignificantincreaseof146.543.971 million in Q4 2023[38] - Product revenue for Q4 2024 reached 107.347million,up148.543.137 million in the same quarter last year[38] - For the full year 2024, total revenue was 329.004million,representinga40.6233.662 million in 2023[38] Financial Performance - The company reported a net income of 23.3millionforQ42024,comparedtoanetlossof14.4 million in Q4 2023[6] - The company achieved a net income of 23.330millioninQ42024,comparedtoanetlossof14.416 million in Q4 2023[38] - Cash, cash equivalents, and investment securities totaled 311.0millionasofDecember31,2024[6]−Cash,cashequivalents,andinvestmentsecuritiesincreasedto311.001 million as of December 31, 2024, up from 217.508millionayearearlier[39]−Totalassetsroseto577.690 million in 2024, compared to 329.587millionin2023[39]−Thecompany’stotalequityincreasedto222.364 million in 2024, up from 160.502millionin2023[39]Expenses−TotalresearchanddevelopmentexpensesforQ42024wereapproximately23.9 million, up from 17.4millioninQ42023[6]−ResearchanddevelopmentexpensesforQ42024were23.874 million, compared to 17.449millioninQ42023,reflectinga36.539.0 million, compared to 31.2millioninQ42023[6]−Selling,generalandadministrativeexpensesforQ42024totaled38.963 million, an increase of 25.2% from $31.152 million in Q4 2023[38] Product Development - The company obtained three additional patents for BRIUMVI, extending patent protection through 2042[5] - Five-year data from Phase 3 trials showed that 92% of patients were free from disability progression after five years of BRIUMVI treatment[5] - The company launched a Phase 1 trial for subcutaneous ublituximab in patients with relapsing forms of multiple sclerosis[5] - The company entered into a global license agreement with Precision BioSciences for the development of an allogeneic CD19 CAR T therapy program[5] - TG Therapeutics has received regulatory approvals for BRIUMVI® in the U.S., EU, and UK for treating relapsing forms of multiple sclerosis, indicating strong market potential[30]