Financial Performance - Total revenue for 2024 reached approximately 1.297billion,withCARVYKTInettradesalesof963 million, marking a significant increase from the previous year[6]. - License revenue for the year ended December 31, 2024, was 138.4million,upfrom35.2 million in 2023, reflecting a growth of 293%[8]. - Collaboration revenue for the year was 482.6million,comparedto249.8 million in 2023, representing an increase of 93%[9]. - Net income for the fourth quarter of 2024 was 26.3million,aturnaroundfromanetlossof144.8 million in the same quarter of 2023[18]. - Adjusted net loss for the year was 188.8million,areductionfrom335.7 million in 2023, indicating improved financial performance[19]. - Total revenue for Q4 2024 reached 186.5million,asignificantincreaseof13479.5 million in Q4 2023[25]. - Basic net income per share for Q4 2024 was 0.07,comparedtoalossof0.40 per share in Q4 2023[26]. - Adjusted net loss for Q4 2024 was 59.1million,comparedtoanadjustednetlossof88.5 million in Q4 2023[34]. Cash and Assets - As of December 31, 2024, the company had approximately 1.1billionincashandcashequivalents,providingafinancialrunwayintothesecondquarteroffiscalyear2026[5].−Cashandcashequivalentsattheendof2024were286.7 million, down from 1.28billionattheendof2023,representingadecreaseof781.67 billion in December 2024 from 1.85billioninDecember2023,adeclineof982.1 million for Q4 2024, an improvement from 95.6millioninQ42023[29].Expenses−Researchanddevelopmentexpensesfortheyearwere413.5 million, an increase of 31.3millionfrom2023,primarilyduetocilta−celactivities[13].−Sellinganddistributionexpensesfortheyearwere147.5 million, up from 94.2millionin2023,reflectingincreasedcommercialactivities[15].−Researchanddevelopmentexpensesfortheyear2024totaled413.5 million, an increase from $382.2 million in 2023[25]. Product Performance - Over 5,000 patients have been treated with CARVYKTI to date, demonstrating the product's market penetration[6]. - The Phase 3 CARTITUDE-4 study showed that 89% of evaluable patients achieved minimal residual disease negativity at the 10 threshold within two months[7].