Financial Performance - First-quarter 2025 total net sales were 585.4million,adecreaseof4.2610.8 million in Q1 2024[5] - Life Science segment net sales for Q1 2025 were 228.6million,down5.4356.8 million, a decrease of 3.2% compared to the same period in 2024[7] - Net sales for Q1 2025 were 585.4million,adecreaseof4.4610.8 million in Q1 2024[30] - Gross profit for Q1 2025 was 306.0million,representingagrossmarginof52.364.0 million, a significant decline of 83.3% from 383.9millioninQ12024[30]−BasicearningspershareforQ12025were2.29, compared to 13.46inQ12024[30]MarginsandIncome−First−quartergrossmarginwas52.371.0 million, or 2.54pershare,comparedto65.3 million, or 2.30pershare,inQ12024[11]−Theestimatednon−GAAPoperatingmarginfor2025isnowexpectedtobeapproximately10.0315.0 million, with a margin of 53.8%, compared to 330.9millionand54.2113.7 million, reflecting a 19.4% margin, compared to 108.4million,whichisa17.723.7 million, a 4.0% margin, compared to 44.6million,whichisa7.333.2 million in the current period, compared to 7.1millioninthepreviousperiod[38]−Thecompanyreportedaprovisionforincometaxesof(19.4) million, compared to (107.2)millioninthepreviousperiod[39]CashFlowandAssets−CashreceivedfromcustomersinQ12025was640.0 million, slightly up from 638.3millioninQ12024[34]−NetcashprovidedbyoperatingactivitiesinQ12025was129.9 million, an increase of 86.1% from 69.8millioninQ12024[34]−TotalassetsasofMarch31,2025,were9,526.9 million, up from 9,364.1millionattheendof2024[32]−Totalstockholders′equityincreasedto6,679.4 million as of March 31, 2025, compared to 6,569.3millionattheendof2024[32]MarketOutlook−Bio−Radismoderatingitsfull−year2025outlook,expectingnon−GAAP,currency−neutralrevenuetodeclinebyapproximately1.064.0 million in Q1 2025[9] - The company reported losses from changes in fair market value of equity securities and loan receivable amounting to (31.8)million,comparedto(422.2) million in the previous period[38] GAAP and Non-GAAP Measures - GAAP net income for the current period is 64.0million,representinga10.9383.9 million, which is a 62.9% increase in the previous period[38] - Non-GAAP net income is reported at 71.0million,a12.165.3 million, which is a 10.7% increase from the prior period[38] - GAAP diluted income per share is 2.29,whilenon−GAAPdilutedincomepershareis2.54, compared to 13.45and2.30 respectively in the prior period[38] - The company does not provide a reconciliation of non-GAAP financial expectations to GAAP measures due to the unpredictable nature of future charges[41]