BioCryst Pharmaceuticals(BCRX) - 2025 Q1 - Quarterly Results

EXHIBIT 99.1 BioCryst Reports First Quarter 2025 Financial Results and Provides Business Update —Q1 2025 ORLADEYO net revenue of $134.2 million (+51 percent y-o-y)— —Full year 2025 ORLADEYO revenue guidance increased to$580 million to $600 million— —Company now expects to be profitable for full year 2025, a year ahead of schedule— —Company pays down$75 million of debt; saves approximately $23.5 million over life of loan— —NDA submitted for ORLADEYO oral granules for children with HAE aged 2-11— —U.S. IND ...