Exhibit 99.1 Castle Biosciences Reports First Quarter 2025 Results Q1 2025 revenue increased 21% over Q1 2024 to 88millionR◯R◯Q12025totaltestreportsforourcorerevenuedrivers(DecisionDx−Melanoma,DecisionDx−SCC,TissueCypher)increased33287-297 million from $280-295 million Conference call and webcast today at 4:30 p.m. ET FRIENDSWOOD, Texas - May 5, 2025--Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through i ...