Financial Performance - Net sales for Q1 2025 were 193,646,000,anincreaseof2188,608,000 in Q1 2024[16] - Gross profit for Q1 2025 was 121,619,000,downfrom127,242,000 in Q1 2024, representing a decrease of approximately 4.1%[16] - The net loss for Q1 2025 was 53,094,000,comparedtoanetlossof36,020,000 in Q1 2024, indicating an increase in losses of approximately 47.5%[16] - Operating loss for Q1 2025 was 48,873,000,comparedtoanoperatinglossof29,337,000 in Q1 2024, reflecting a worsening of approximately 66.5%[16] - The company reported a comprehensive loss of 51,348,000forQ12025,comparedtoacomprehensivelossof35,387,000 in Q1 2024, an increase of approximately 45.2%[16] - The Company reported net sales of 193.646millionforthethreemonthsendedMarch31,2025,representinga2.7188.608 million in the same period of 2024[53] - Bone Growth Therapies generated sales of 55.050million,up4.952.477 million in the prior year, while Global Orthopedics sales increased by 9.1% to 29.810millionfrom27.315 million[53] - Total revenues for the three months ended March 31, 2024, were 188,608,000,a2.1184,000,000 in the same period of 2023[64] - Global Spine segment revenues reached 161,293,000,whileGlobalOrthopedicssegmentrevenueswere27,315,000 for the same period[64] Cash and Liquidity - Cash and cash equivalents at the end of Q1 2025 were 57,953,000,comparedto26,964,000 at the end of Q1 2024, showing an increase of approximately 114.5%[18] - The Company had no borrowings on its available lines of credit in Italy, which provide up to an aggregate amount of €5.5 million (5.9million)asofMarch31,2025[30]−TheCompanyenteredintoa275.0 million secured credit agreement on November 7, 2024, with financial covenants requiring maintenance of a minimum liquidity level and a maximum total debt-to-EBITDA leverage ratio[29] Expenses and Losses - Research and development expenses for Q1 2025 were 19,766,000,slightlyupfrom19,492,000 in Q1 2024, indicating a growth of approximately 1.4%[16] - The allowance for expected credit losses increased to 8.602millionasofMarch31,2025,comparedto8.398 million at the end of March 2024[55] - The Company accrued 8.9millionrelatedtotheItalianMedicalDevicePayback(IMDP)asofMarch31,2025,withexpensesof0.3 million recorded for both the three months ended March 31, 2025, and 2024[49] - Share-based compensation expenses totaled 6,469,000forthethreemonthsendedMarch31,2025,downfrom8,800,000 in the same period of 2024[69] - The company recognized impairment charges of 29,026,000relatedtothediscontinuedM6productlinesduringthethreemonthsendedMarch31,2025[77]−Amortizationofacquiredintangibleswas18,355,000 for the three months ended March 31, 2025, compared to 4,226,000inthesameperiodof2024[68]InventoryandAssets−AsofMarch31,2025,totalinventoriesdecreasedto174,480,000 from 189,452,000asofDecember31,2024,representingadeclineofapproximately7.531,727,000, down from 32,624,000asofDecember31,2024,indicatingareductionofabout2.7156,885,000, slightly decreasing from 157,015,000asofDecember31,2024,achangeofapproximately0.114,790,000, down from 15,400,000atthebeginningoftheyear,reflectingadecreaseofabout4.08,355,000, up from 6,760,000atthebeginningoftheyear,indicatinganincreaseofapproximately23.519.516 million, while the total adjusted EBITDA for the Company was 19.489millionforthethreemonthsendedMarch31,2025[63]−AdjustedEBITDAforthetotalsegmentswas18,398,000, with Global Spine contributing 19,889,000andGlobalOrthopedicsshowingalossof1,491,000[64]