Financial Performance - Revenues for Q1 2025 increased by 92million,or2.53,829 million compared to Q1 2024, driven by a constant currency revenue growth of approximately 129million,or3.53,829 million, an increase of 92million,or2.53,737 million in the same period of 2024[99] - Income from operations for Q1 2025 was 558million,whilenetincomewas173 million[136] Cost and Expenses - Cost of revenues, exclusive of depreciation and amortization, rose by 87millionto2,531 million, representing 66.1% of revenues, compared to 65.4% in Q1 2024[90] - Selling, general and administrative expenses remained consistent at 508million,accountingfor13.3137 million, or 5.6%, for Q1 2025[90] - Restructuring costs increased to 29millioninQ12025from15 million in Q1 2024, aimed at streamlining global operations and integrating acquisitions[93] Segment Performance - Technology & Analytics Solutions contributed a 110 million increase in revenues, while Contract Sales & Medical Solutions saw a 4 million decrease[89] - Technology & Analytics Solutions segment revenues increased by 93million,or6.41,546 million, driven by constant currency growth of approximately 110million,or7.62,102 million, a slight increase of 7million,or0.323 million, or 1.1%[108] - Contract Sales & Medical Solutions segment revenues decreased by 8million,or4.2181 million, primarily due to volume-related decreases in services performed[114] - The total segment profit for the first quarter of 2025 was 496million,comparedto506 million in the same period of 2024[99] - Research & Development Solutions' contracted backlog increased from 31.1billionto31.5 billion, with an expected revenue conversion of approximately 7.9billioninthenexttwelvemonths[107]TaxandEquity−TheeffectiveincometaxrateforQ12025was18.913 million in Q1 2025 from 3millioninQ12024,reflectingoperationalresultsofunconsolidatedaffiliates[98]CashFlowandFinancing−CashbalanceasofMarch31,2025,was1,740 million, an increase from 1,702millionasofDecember31,2024[119]−Netcashprovidedbyoperatingactivitiesincreasedby46 million to 568millioninthefirstquarterof2025,drivenbyincreasesincashfromaccountsreceivableandunbilledservices[127]−Thecompanyrepurchased2.3millionsharesfor425 million under its equity repurchase program, with remaining authorization to repurchase up to 2,588million[122]−Netcashusedinfinancingactivitiesincreasedby152 million to (258)millioninQ12025comparedto(106) million in Q1 2024, primarily due to higher cash payments on debt and stock repurchases[129] - Cash payments for debt and principal payments on finance leases totaled 2,053millioninQ12025[129]IndebtednessandAssets−TotalindebtednessasofMarch31,2025,was14,389 million, with 895millionofadditionalavailableborrowingsundertherevolvingcreditfacility[123]−Totalcurrentassetsdecreasedfrom935 million as of December 31, 2024, to 629millionasofMarch31,2025[136]−Totalcurrentliabilitiesslightlyincreasedfrom3,792 million as of December 31, 2024, to 3,809millionasofMarch31,2025[136]−Totalnoncurrentliabilitiesincreasedfrom12,333 million as of December 31, 2024, to 12,626millionasofMarch31,2025[136]−Amountsduefromnon−Guarantorsubsidiariesdecreasedfrom4,952 million to 3,718millionfromDecember31,2024,toMarch31,2025[136]DebtIssuance−Thecompanyissued1,250 million in 6.250% senior secured notes due 2029 and 750millionin5.7002,000 million in gross proceeds[130] Currency Impact - Approximately 30% of revenues in Q1 2025 were denominated in currencies other than the US dollar, impacting financial results due to foreign currency fluctuations[87] Corporate Governance - The company reported no material changes to its critical accounting policies or market risk disclosures compared to the previous year[139][140] AI Commitment - The company is committed to using AI responsibly, with a focus on privacy, regulatory compliance, and patient safety in its service offerings[82]