Revenue Performance - Total revenue for Q1 2025 was 48million,a2738 million in the same period last year, primarily due to a 7millionnon−cashrevenuerelease[6].−CellEngineeringrevenueforQ12025was31 million, up 10% from 28millionintheprioryear,drivenbygrowthwithbiopharmaandgovernmentcustomers[6].−CellEngineeringrevenueincreasedto38,230,000 in Q1 2025 from 27,889,000inQ12024,representingagrowthof37.548,318,000, up from 37,944,000inQ12024,markinga27.5167-187million,withCellEngineeringrevenueprojectedat117-137million[12].FinancialLossesandImprovements−GAAPnetlossforQ12025was(91) million, an improvement from (166)millioninthesameperiodlastyear[6].−Netlossnarrowedto90,957,000 in Q1 2025 compared to a net loss of 165,911,000inQ12024,improvingby45.0(1.68) in Q1 2025 from (3.31)inQ12024[19].−AdjustedEBITDAforQ12025was(47) million, an improvement from (117)millionintheprioryear,attributedtoincreasedrevenueanddecreasedoperatingexpenses[6].−AdjustedEBITDAforQ12025was(47,451,000), an improvement from (117,001,000)inQ12024[29].−ThetotalsegmentoperatinglossforQ12025was(36,773,000), compared to (103,471,000)inQ12024,reflectingasignificantreductioninlosses[25].CostManagement−Thecompanyaimstoachieve250 million in annualized cost reductions by the end of Q3 2025, with a current run-rate cost reduction of 205million[6].−Researchanddevelopmentexpensesdecreasedto70,923,000 in Q1 2025 from 136,457,000inQ12024,areductionof48.0137,286,000 in Q1 2025 from 215,946,000inQ12024,adeclineof36.45,273,000 in Q1 2025, primarily related to employee termination costs[26]. Cash and Backlog - Cash, cash equivalents, and marketable securities as of March 31, 2025, totaled 517million[6].−CashandcashequivalentsattheendofQ12025were312,420,000, down from 840,440,000attheendofQ12024[23].−Ginkgohasacontractedbacklogofapproximately180 million across 28 US Government projects in Cell Engineering and Biosecurity[6]. Market Position and Growth - Ginkgo's Datapoints and Automation offerings are gaining traction, including a new deal with Aura Genetics, marking its first diagnostics company customer[6]. - The company is well-positioned in the biotechnology sector, which is emphasized as a critical area of national importance by US government reports[6].