Financial Performance - Total revenues for Q1 2025 were 6,667million,aslightdecreaseof0.36,686 million in Q1 2024[15] - Product sales amounted to 6,613millioninQ12025,downfrom6,647 million in Q1 2024, reflecting a decrease of 0.5%[15] - Net income for Q1 2025 was 1,315million,asignificantrecoveryfromanetlossof4,170 million in Q1 2024[15] - Operating income for Q1 2025 was 2,237million,comparedtoanoperatinglossof4,322 million in the same period last year[15] - Basic earnings per share attributable to Gilead for Q1 2025 was 1.06,arecoveryfromalossof3.34 per share in Q1 2024[15] - Gilead's income before income taxes for Q1 2025 was 1,649million,comparedtoalossof4,486 million in Q1 2024[86] Cash Flow and Investments - Cash provided by operating activities for the three months ended March 31, 2025, was 1,757million,downfrom2,219 million in the same period of 2024[24] - Net cash used in investing activities was 415millionforQ12025,comparedto2,207 million in Q1 2024, indicating a reduction in cash outflow[24] - The company reported a net cash used in financing activities of 3,426millionforQ12025,anincreasefrom1,361 million in Q1 2024[24] - Cash and cash equivalents at the end of the period were 7,926million,upfrom4,718 million at the end of Q1 2024[24] - Total cash and cash equivalents at the beginning of the period were 9,991million,reflectingastrongliquidityposition[24]AssetsandLiabilities−Totalcurrentassetsdecreasedto16,901 million as of March 31, 2025, down from 19,173millionasofDecember31,2024[13]−Totalassetsdecreasedto56,434 million as of March 31, 2025, compared to 58,995millionasofDecember31,2024[13]−Long−termdebtdecreasedto22,146 million as of March 31, 2025, down from 24,896millionasofDecember31,2024[13]−AsofMarch31,2025,totaldebt,netamountedto24,952 million, a decrease from 26,710millionasofDecember31,2024[69]−Thecompanyrepaid1.75 billion of principal balance related to senior unsecured notes due at maturity in February 2025[70] Research and Development - Research and development expenses decreased to 1,379millioninQ12025from1,520 million in Q1 2024, a reduction of approximately 9.3%[15] - A partial impairment charge of 2.4billionwasrecordedforcertainacquiredin−processresearchanddevelopmentassetsduringthethreemonthsendedMarch31,2024[38]−Apartialimpairmentchargeof2.4 billion was recognized for the NSCLC IPR&D intangible asset due to a failed Phase 3 study[58] Legal and Regulatory Matters - The company intends to vigorously defend against various lawsuits, including those related to product liability involving approximately 22,000 active plaintiffs[79] - The company is involved in litigation with generic manufacturers regarding the exclusivity of its products, which could significantly impact revenues[73] - The company has approximately 220millioninaccrualsforlegalmattersasofMarch31,2025,downfrom242 million as of December 31, 2024[72] - A settlement agreement was reached in April 2025 with the U.S. Attorney's Office for the Southern District of New York related to a government investigation[80] - The company accrued approximately 200millionforasettlementwiththeU.S.Attorney′sOfficefortheSouthernDistrictofNewYorkinApril2025[72]SegmentPerformance−ProductsalesintheHIVsegmenttotaled4,587 million for Q1 2025, up from 4,342millioninQ12024,representinganincreaseof5.654 million in royalty, contract, and other revenues for Q1 2025, compared to 39millioninQ12024[29]Expenses−Sellingandmarketingexpensesincreasedto753 million in Q1 2025 from 743millioninQ12024,whilegeneralandadministrativeexpensesdecreasedto505 million from 632million[89]−Gilead′stotalselling,general,andadministrativeexpensesforQ12025were1,258 million, down from 1,375millioninQ12024[89]−Other(income)expense,netreportedalossof328 million in Q1 2025, compared to a gain of 91millioninQ12024[68]TaxMatters−TheeffectivetaxrateforQ12025was20.23.9 billion of non-deductible acquired IPR&D expenses related to the acquisition of CymaBay[87] Other Financial Metrics - Unrealized losses related to equity securities amounted to 436millionforthethreemonthsendedMarch31,2025,comparedto15 million in the same period of 2024[44] - The fair value of the contingent consideration liability related to the acquisition of MYR GmbH increased to 216millionasofMarch31,2025,from206 million at the beginning of the period[36] - The total estimated fair value of senior unsecured notes was 21.886billionasofMarch31,2025,downfrom23.335 billion at the end of 2024[39] - The liability related to future royalties from the acquisition of Immunomedics, Inc. was approximately 0.9billionasofMarch31,2025[40]AcquisitionsandInvestments−Gileadmadea250 million upfront payment to LEO Pharma for a strategic partnership to develop STAT6 programs, with potential additional milestone payments of up to 1.5billion[54]−Gileadacquiredapproximately15.2millionadditionalsharesofArcusfor320 million, increasing its stake to approximately 30%[55] - The acquisition of CymaBay Therapeutics, Inc. was completed for total consideration of $3.9 billion in March 2024[51] Subsequent Events - There were no subsequent events or transactions to disclose beyond those already mentioned in the financial statements[90]