Biodesix Announces Publication of a New Nodify CDT® Clinical Validation Study

Core Insights - The article discusses the validation of the Nodify CDT blood-based lung nodule test, reaffirming its performance in detecting lung cancer through a study published in CHEST Pulmonary Journal [1] Company Overview - Biodesix, Inc. is a leading diagnostic solutions company focused on lung disease, offering five Medicare-covered tests for patients with lung diseases [2] - The company’s Nodify Lung Nodule Risk Assessment combines the Nodify CDT and Nodify XL2 tests to evaluate the risk of malignancy in pulmonary nodules, aiding physicians in patient triage [2] Test Performance - The Nodify CDT test measures levels of seven autoantibodies associated with lung cancer, providing a "rule in" test for likely cancerous nodules [1] - In a study of 447 patients, 33% of those with cancerous nodules were diagnosed more than three months after detection, indicating missed opportunities for early diagnosis [1] - The Nodify CDT test demonstrated high specificity, with a low percentage of benign nodules misclassified as high risk, outperforming positron emission tomography (PET) scans which had more false positives [1] Clinical Implications - The study suggests that the Nodify CDT test may serve as a useful adjunct in clinical practice, potentially avoiding delays in treatment for patients with cancer [1] - The findings highlight the inadequacy of relying solely on PET scans for diagnostic decision-making in lung nodule risk assessment [1]