Core Insights - Johnson & Johnson (J&J) reported fourth-quarter 2024 earnings of 2.04pershare,exceedingtheZacksConsensusEstimateof2.00, but reflecting a 10.9% decline year over year [1] - Total sales for the quarter reached 22.52billion,slightlysurpassingtheZacksConsensusEstimateof22.51 billion, with a year-over-year increase of 5.3% [2] Financial Performance - Adjusted earnings, excluding intangible amortization and special items, were reported at 1.41pershare,down17.188.82 billion, slightly missing the Zacks Consensus Estimate of 88.84billion[16]SegmentPerformance−TheInnovativeMedicinessegmentsawsalesrise4.414.33 billion, driven by key products like Darzalex and new drugs such as Carvykti and Tecvayli [5][6] - MedTech segment sales reached 8.19billion,up6.78.25 billion [14] Market Dynamics - Domestic sales increased by 10% to 13.2billion,whileinternationalsalesdeclinedby0.79.32 billion, impacted by currency fluctuations [3] - The Innovative Medicines unit outperformed expectations, while the MedTech unit faced challenges, particularly in the Asia Pacific region due to competitive pressures and government cost containment efforts in China [15][19] Future Outlook - For 2025, J&J expects sales in the range of 89.2billionto90.0 billion, which is below the Zacks Consensus Estimate of 91.2billion,indicatingagrowthof0.510.50 and 10.70,suggestingagrowthof5.214.6 billion, which will enhance its neuroscience pipeline [23][22]