Core Insights - Danaher Corporation's fourth-quarter 2024 adjusted earnings per share were 2.14,missingtheZacksConsensusEstimateof2.17, but reflecting a year-over-year increase of 2.4% [1] - The company reported net sales of 6.5billion,exceedingtheconsensusestimateof6.4 billion, with a year-over-year increase of 2.1% driven by strong performance in the Diagnostics and Life Sciences segments [2] Segment Performance - Life Sciences segment revenues reached 2.03billion,up5.5376 million [3] - Diagnostics segment revenues totaled 2.64billion,down3624 million [4] - Biotechnology segment revenues were 1.87billion,up6.5508 million [5] Financial Metrics - Danaher's cost of sales increased by 0.8% year over year to 2.6billion,whilegrossprofitrose3.83.4 billion, resulting in a gross margin of 59.5% [6] - Operating profit increased by 6.6% year over year to 1.43billion,althoughtheoperatingmargincontractedto21.82.1 billion, down from 5.9billionattheendof2023,whilelong−termdebtdecreasedto15.5 billion from 16.7billion[8]−Thecompanygeneratednetcashof6.68 billion from operating activities, up from 6.49billioninthepreviousyear,withadjustedfreecashflowincreasing3.55.31 billion [9] Outlook - For the first quarter, Danaher anticipates adjusted core sales from continuing operations to decline in low-single digits year over year, with an expected increase of approximately 3% year over year in 2025 [10]