Core Insights - Charles River Laboratories International, Inc. (CRL) reported fourth-quarter 2024 adjusted earnings per share (EPS) of 2.66,anincreaseof8.14.22 per share compared to earnings of 3.62pershareinthesamequarterlastyear[2]−Full−year2024EPSwas10.32, down 3.3% from the previous year but still surpassing the Zacks Consensus Estimate by 1.6% [2] Revenue Performance - Total revenues for the fourth quarter reached 1.00billion,beatingtheZacksConsensusEstimateby2.74.05 billion, a decrease of 1.9% year over year, yet exceeding the Zacks Consensus Estimate by 0.7% [3] Segment Analysis - Research Models and Services (RMS) revenues in Q4 were 204.3million,up4.3603.3 million, down 3.6% year over year and 3.5% organically [6] - Manufacturing Solutions revenues reached 194.9million,anincreaseof1.6284.2 million, a decline of 21.9% from the previous year, with a gross margin of 28.4%, down 757 basis points [8] - Adjusted operating income was 88.5million,reflectinga47194.6 million, down from 276.8millionattheendof2023[9]−Cumulativenetcashprovidedbyoperatingactivitieswas734.6 million, compared to 683.9millionayearago[10]FutureGuidance−For2025,CRLexpectstotalrevenuestodeclineby4.5−7.03.89 billion, indicating a reported decline of 3.4% [11] - Adjusted EPS for 2025 is projected to be in the range of 9.10−9.60, with the Zacks Consensus Estimate at $9.93 [11] Overall Assessment - The company reported better-than-expected results in Q4 2024, with both earnings and revenues surpassing estimates, despite a year-over-year decline in total revenues [12] - While RMS and Manufacturing Solutions segments showed growth, the DSA segment faced significant declines due to lower sales volume [13] - The company is focusing on innovation and enhancing its portfolio to adapt to changing industry demands [14]