Core Insights - Glaukos Corporation reported a narrower adjusted loss of 40 cents per share for Q4 2024, better than the Zacks Consensus Estimate of a 43 cents loss and improved from a 63 cents loss in the same quarter last year [1] - The company achieved revenues of 105.5millioninQ42024,reflectinga28.184.1 million, marking a 39% year-over-year increase, while sales in Corneal Health remained stable [3] Margin Analysis - Gross profit rose by 21.1% year-over-year to 76.9million,withanadjustedgrossmarginof8269 million, while research and development expenses decreased by 1.4% to 36.5million[4]FinancialUpdate−GlaukosendedQ42024withcashandcashequivalentsandshort−terminvestmentstotaling324 million, up from 267.2millionattheendofQ32024[6]2025Guidance−Thecompanyexpects2025revenuestobebetween475 million and 485million,significantlyhigherthanthepreviousguidanceof370 million to 376million,withalosspershareestimateof1.08, indicating a 42.8% improvement year-over-year [7] Operational Highlights - The glaucoma franchise's revenue growth was driven by the iStent portfolio and increasing contributions from iDose TR, with plans to enhance market access for iDose TR in 2025 [9] - Glaukos is advancing its product pipeline, including an NDA submission for Epioxa, with expected approval by the end of 2025, and is conducting a phase 2b/3 clinical trial for iDose TREX [10][11] Market Performance - Following the Q4 results, shares of Glaukos fell by 13.6% in after-market trading, although the stock has gained 6.1% year-to-date, contrasting with a 0.1% decline in the industry [12]