JNJ vs. PFE: Which Drug Giant is a Better Buy Now?

Core Viewpoint - Johnson & Johnson (J&J) and Pfizer (PFE) are two leading pharmaceutical companies with diverse healthcare portfolios, each facing unique growth prospects and challenges in the current market environment [1][2]. Group 1: Johnson & Johnson (J&J) - J&J's diversified business model, operating through over 275 subsidiaries, allows it to better withstand economic cycles [3]. - The Innovative Medicine unit reported a 5.8% organic sales growth in 2024, with expectations for continued growth in 2025 despite challenges such as the loss of exclusivity for Stelara, which generated 10.36 billion in sales in 2024 [4][7]. - J&J is actively enhancing its pipeline through acquisitions and has made significant progress in this area [5]. - The MedTech business is experiencing headwinds, particularly in China, due to the volume-based procurement program and anti-corruption campaigns, with no expected improvement in 2025 [6]. - J&J is facing over 62,000 lawsuits related to its talc-based products, with a recent bankruptcy court ruling rejecting its proposed settlement plan [8]. - As of the end of 2024, J&J had cash and cash equivalents of 24.5 billion against long-term debt of $30.65 billion, resulting in a debt-to-capital ratio of 0.3, lower than the industry average of 0.41 [9]. Group 2: Pfizer (PFE) - Pfizer is a major player in oncology, bolstered by the acquisition of Seagen in 2023, and is transitioning from a period of revenue volatility due to COVID-related uncertainties [10]. - Non-COVID product revenues increased by 12$6.0 billion through restructuring [12]. - The company faces challenges, including declining sales of COVID-19 products and anticipated patent expirations from 2026 to 2030, which may impact key products [13]. - As of December 31, 2024, Pfizer had cash and cash equivalents of $20.48 billion and long-term debt of$57.4 billion, resulting in a debt-to-capital ratio of 0.42, in line with the industry average [14]. Group 3: Financial Estimates and Performance - The Zacks Consensus Estimate for J&J's 2025 sales and EPS indicates a year-over-year increase of 1.4% and 6.0%, respectively, with stable EPS estimates of $10.58 for 2025 and$11.07 for 2026 [15]. - In contrast, Pfizer's 2025 sales and EPS estimates imply a year-over-year decline of 0.7% and 4.5%, respectively, although EPS estimates have been trending upward [17]. - Year-to-date, J&J's stock has risen by 8.3%, while Pfizer's stock has declined by 5.4%, compared to the industry's increase of 1.6% [20]. - From a valuation perspective, Pfizer's shares trade at a forward P/E ratio of 8.30, significantly lower than the industry average of 15.78, while J&J's shares trade at 14.51 [22][23]. - J&J offers a dividend yield of 3.2%, while Pfizer's yield is around 7%, with J&J's return on equity at 34.2%, higher than Pfizer's 19.6% [24]. Group 4: Investment Considerations - Both companies hold a Zacks Rank of 3 (Hold), indicating a challenging decision for investors [25]. - J&J has demonstrated steady revenue and EPS growth, but concerns exist regarding its MedTech unit and ongoing legal issues [26]. - Pfizer, with improving growth prospects, rising estimates, and a higher dividend yield, may present a more attractive option for near-term investors seeking growth in the drug/biotech sector [27].