Core Insights - Metagenomi, Inc. has made significant advancements in gene editing technologies, particularly for treating neurological disorders through extrahepatic in vivo gene editing [1][2] - The company presented three abstracts at the ASGCT 28 Annual Meeting, showcasing its proprietary gene editing toolbox, including compact nucleases and CRISPR-associated transposases (CAST) [1][2] Gene Editing Technologies - The metagenomics discovery platform utilizes natural microbial evolution and AI-guided protein optimization to identify and enhance novel gene editing systems [2] - Compact Type II and Type V nucleases have been developed for efficient in vivo editing, with a focus on delivering large therapeutic genes [2][9] - The CAST system has shown promise in addressing challenges related to targeted and precise large gene integration [2] Presentation Highlights - A compact type II CRISPR system (MG21-1) demonstrated up to 69% target protein reduction in the CNS with localized AAV9 delivery [6] - An ultra-compact type V nuclease (MG119-28) achieved over 50% restoration of dystrophin protein levels in DMD model myocytes and 64% knockdown of target protein in the motor cortex [6] - The type V-K CAST system has improved integration efficiency by over 50 times compared to natural systems, indicating its potential for therapeutic applications [9] Company Overview - Metagenomi leverages AI and machine learning to develop next-generation genome editing therapeutics, analyzing over 7.4 billion proteins to target various genetic mutations [7] - The company has a lead program in Hemophilia A, aiming to provide lifelong protection from bleeding events and joint damage [7]

Core Insights - Titan Mining Corporation reported a 37% year-over-year revenue increase for Q1 2025, reaching $16.02 million, alongside a 4% reduction in all-in sustaining costs (AISC) [1][7] - The company achieved a payable zinc production of 15.37 million pounds, a 5% increase from Q1 2024, and a significant cash flow from operations of $2.69 million, up 922% year-over-year [7][8] - Exploration results indicate potential mineral resource expansion, with a notable intercept of 11.6 feet at 13.7% Zn, approximately 1,750 feet outside the current mineral resource model [4][11] Financial Performance - Revenue for Q1 2025 was $16.02 million, a 37% increase compared to $11.73 million in Q1 2024 [7] - Net income after tax was $0.35 million, compared to a loss of $2.63 million in Q1 2024 [7] - Cash flow from operating activities was $2.69 million, significantly up from $0.26 million in Q1 2024 [7] Operational Highlights - The average realized zinc price was $1.29 per pound, up from $1.11 per pound in Q1 2024 [7] - C1 cash costs decreased to $0.91 per pound, down 6% from $0.97 per pound in Q1 2024, while AISC was $0.96 per pound, down 4% from $1.00 per pound in Q1 2024 [7][8] - The company drilled 22 holes totaling 9,213 feet in underground exploration, focusing on the Mahler, New Fold, and Mud Pond zones [11] Strategic Developments - Titan is advancing its dual-commodity growth plan with robust cash flow from zinc operations and rapid progress on the Kilbourne graphite project [5][10] - The Kilbourne Graphite Project is on track to produce 1,000–1,200 tonnes of graphite concentrate per year, with plans to increase production to 40,000 tonnes per year, marking the first fully integrated natural flake graphite production in the U.S. since 1956 [10][28] - The company is implementing a production expansion from 1,750 to 2,250 tons/day, expected to be completed by year-end [9][28]

Earnings Call Scheduled for 8:30 a.m. U.S. Eastern Time on Wednesday, May 21, 2025HONG KONG, May 14, 2025 (GLOBE NEWSWIRE) -- UCLOUDLINK GROUP INC. (“UCLOUDLINK” or the “Company”) (NASDAQ: UCL), the world’s first and leading mobile data traffic sharing marketplace, today announced that it will report its unaudited financial results for the first quarter ended March 31, 2025, before U.S. markets open on Wednesday, May 21, 2025. Management will hold a conference call to discuss these results at 8:30 a.m. U.S. ...

SHENZHEN, China, May 14, 2025 (GLOBE NEWSWIRE) -- LexinFintech Holdings Ltd. (“Lexin” or the “Company”) (NASDAQ: LX), a leading credit technology-empowered consumer financial service enabler in China, today announced that it will report its unaudited financial results for the first quarter ended March 31, 2025, after the U.S. market closes on Wednesday, May 21, 2025. The Company’s management will host an earnings conference call at 10:00 PM U.S. Eastern time on May 21, 2025 (10:00 AM Beijing/Hong Kong time ...

Core Insights - Eika Boligkreditt AS has released its interim report for the first quarter of 2025, which is accessible online [1] Group 1 - The report provides detailed financial performance metrics for Eika Boligkreditt AS during the first quarter of 2025 [1]

Core Viewpoint - BlackRock Canada announced the May 2025 cash distributions for various iShares ETFs, detailing specific amounts for each fund and the payment schedule for unitholders [1][2][4]. Distribution Details - The cash distribution amounts per unit for selected iShares ETFs are provided, with notable distributions including: - iShares S&P/TSX 60 Index ETF (XIU): $0.272 - iShares Canadian Real Return Bond Index ETF (XRB): $0.273 - iShares Flexible Monthly Income ETF (XFLI): $0.189 - iShares S&P/TSX Composite High Dividend Index ETF (XEI): $0.136 [2][3]. Payment Schedule - Unitholders of record for most iShares ETFs will receive distributions on May 30, 2025, while unitholders of XRB will receive distributions on June 5, 2025 [1][4]. Additional Information - BlackRock Canada plans to issue a press release around May 21, 2025, to provide final amounts for the iShares Premium Money Market ETF [4]. - The iShares Canadian Real Return Bond Index ETF also has reinvested distributions, with a unit value of $0.31014 [6]. Company Overview - BlackRock is a leading provider of financial technology and investment management, with over $4.3 trillion in assets under management as of March 31, 2025 [8]. - iShares ETFs, managed by BlackRock, offer a diverse range of investment opportunities across various markets [8].

Core Insights - Afarak Group's production in Q1 2025 increased by 15.2% compared to the same period last year [2][3] Production Summary - Speciality Alloys production reached 26,961 metric tons (mt) in Q1 2025, up from 23,411 mt in Q1 2024, reflecting a 15.2% increase [3] - Processing volumes increased by 7.4%, with Q1 2025 figures at 7,411 mt compared to 6,901 mt in Q1 2024 [4][3] - Mining production saw an overall increase of 18.4% in Turkish mines, with Q1 2025 production at 19,550 mt compared to 16,510 mt in Q1 2024 [3][7] - However, South African mining activity dropped significantly by 26.8%, with Q1 2025 production at 51,413 mt compared to 70,278 mt in Q1 2024, attributed to heavy rainfall affecting operations [3][7]

Core Viewpoint - Valeura Energy Inc. reported strong financial and operational results for Q1 2025, highlighting a significant increase in adjusted cash flow from operations and a robust balance sheet, despite a decrease in oil production and revenue compared to the previous quarter. Financial Performance - Adjusted cash flow from operations reached US$74 million, a 55% increase compared to Q1 2024, attributed to a more tax-efficient corporate structure [3][14] - Oil revenue for Q1 2025 was US$148 million, essentially unchanged from Q1 2024, despite a 36% decrease in oil volumes sold [6][12] - Net income for Q1 2025 was US$14 million, a 93% decrease compared to the previous quarter [6] Operational Highlights - Average daily oil production was 23,853 bbls/d, an 8% increase year-over-year, but an 11% decrease from the previous quarter [6][10] - Adjusted operating expenses per barrel decreased to US$24.1, an 8% improvement compared to Q1 2024 [7][13] - The company maintained a strong cash position of US$239 million with no debt as of March 31, 2025 [5][16] Production and Inventory - Total working interest share production before royalties was 2.15 million bbls, an 8% increase from Q1 2024 [10] - Oil sales totaled 1.88 million bbls, leading to an increase in oil inventory to 0.89 million bbls by the end of Q1 2025 [11] Strategic Initiatives - The company is pursuing both organic and inorganic growth opportunities, with ongoing production operations across all fields in the Gulf of Thailand [5][17] - A positive final investment decision was made for the Wassana field redevelopment project, targeting production start in Q2 2027 [22][23] Future Outlook - Valeura expects to meet its production guidance range for 2025 of 23,000 – 25,500 bbls/d, supported by ongoing drilling campaigns and operational improvements [17][52]

Bids, sales, stop-rates and prices are presented in the table below: ISINBid Mill. kr. (nominal)SaleStop-rate (per cent)Pro-rataPrice98 19906 DKT 02/09/25 III1000---Total1000 The sale will settle 16 May 2025. ...

Core Insights - Clarivate Plc has introduced Pathway Maps in its OFF-X platform, enhancing translational safety intelligence in drug development [1][3] - Over 30% of drug development failures are linked to safety issues, necessitating earlier identification of potential liabilities [1][2] - The integration of visual disease biology with comprehensive safety data allows researchers to make faster, more informed decisions [2][3] Company Overview - Clarivate is a global provider of transformative intelligence, offering data, insights, analytics, and workflow solutions across various sectors including Life Sciences & Healthcare [5] - The company aims to empower researchers with tools that streamline workflows and provide actionable insights to improve patient outcomes [3][5] Product Features - OFF-X supports researchers throughout the drug development lifecycle, from early discovery to post-marketing surveillance [4] - The platform combines proprietary physiological and disease pathway visualizations with curated safety data, enhancing risk evaluation [3][4] - The addition of Pathway Maps allows for disease-specific visualizations of key signaling pathways, facilitating quicker identification of safety liabilities [2][3]