Financial Data and Key Metrics Changes - The company reported fourth quarter revenue of 1.69billion,reflectinglowsingle−digitorganicgrowth,markingasignificantmilestoneinmarketrecovery[24][25]−AdjustedEBITDAmarginexpandedto18.20.27, up 4% sequentially and 8% year-over-year [10][29] - For the full year, reported revenue was 6.78billion,representinga21.13 billion in revenue for Q4, a 1% decline on an organic basis, while full-year revenue was 4.61billion,down2561 million in Q4 revenue, with organic growth of over 4%, driven by high single-digit growth in bioprocessing [36][37] Market Data and Key Metrics Changes - The academic end market remains strong, with large pharma customers increasing investments in preclinical activities, supporting growth in 2025 [12][13] - The company noted a return to normalcy in customer engagement across its base, indicating a positive trend in market conditions [11] Company Strategy and Development Direction - The company is focused on de-leveraging, aiming to bring adjusted net leverage below 3 times, having paid down 1.3billionofdebtin2024[21][30]−Abalanced,value−drivencapitalallocationapproachisplannedpost−de−leveraging,withafocusoninnovation−drivengrowthandmarginexpansion[22][56]−Theintroductionofnewproductsandservices,includingdigitaltoolsandgenerativeAI,ispartofthelong−termgrowthstrategy[15][16]Management′sCommentsonOperatingEnvironmentandFutureOutlook−Managementexpressedconfidenceinthebusinessenvironmentfor2025,anticipatingorganicrevenuegrowthandcontinuedmarginexpansion[57][58]−ThecompanyexpectsadjustedEBITDAmarginstoimprovetoapproximately18768 million in free cash flow for the year, exceeding original guidance [32] - The clinical services divestiture is expected to impact revenue and margins, with a 2% headwind anticipated in 2025 [39][43] Q&A Session Summary Question: Trends in bioprocessing orders and guidance - Management noted strong order intake in bioprocessing with high single-digit growth in Q4, indicating no significant pull forward of orders [60][62] Question: Clarification on margin guidance - Management explained the wide margin range for 2025 is due to fixed costs and potential sales performance at the top end of the range [66][72] Question: Performance of the lab business - Management acknowledged a muted seasonal ramp in the lab business, attributing it to macro factors and holiday timing [78][80] Question: Impact of new administration on guidance - Management indicated it is early to assess the impact of the new administration but remains optimistic about a business-friendly environment [84][88] Question: Advanced technologies and semiconductors outlook - Management stated that the semiconductor market remains a small part of the business, with expectations of stability rather than recovery in 2025 [110][112] Question: M&A strategy and future flexibility - Management confirmed that while debt reduction is a priority, M&A remains part of the long-term strategy, with flexibility expected once leverage targets are met [122][124]