Core Viewpoint - Agenus (AGEN) has experienced a decline of 7.9% over the past week, but the formation of a hammer chart pattern suggests potential support and a possible trend reversal in the future [1][2]. Technical Analysis - A hammer chart pattern indicates a minor difference between opening and closing prices, with a long lower wick, suggesting that the stock may have found support after a downtrend [3][4]. - The occurrence of a hammer pattern at the bottom of a downtrend signals that bears may have lost control, indicating a potential trend reversal [4]. Fundamental Analysis - There is rising optimism among Wall Street analysts regarding AGEN's future earnings, which enhances the prospects for a trend reversal [2][6]. - The consensus EPS estimate for the current year has increased by 7.4% over the last 30 days, indicating analysts' agreement on the company's potential for better earnings [7]. - AGEN holds a Zacks Rank of 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks, which typically outperform the market [8].

Financial Performance - Research and development revenue decreased to approximately $0.5 million in 2024 from $38.8 million in 2023, primarily due to a $25.0 million milestone earned in 2023 under the BMS License Agreement [440]. - Non-cash royalty revenue related to the sale of future royalties from GSK decreased by $13.6 million to approximately $101.0 million in 2024, down from $114.6 million in 2023, attributed to decreased net sales of GSK's vaccines containing the QS-21 STIMULON adjuvant [441][442]. - The accumulated deficit as of December 31, 2024, reached $2.18 billion, indicating significant losses since inception [438]. - R&D expenses decreased by 34% to $155.5 million for the year ended December 31, 2024, down from $234.6 million in 2023, primarily due to a $52.7 million decrease in third-party services and a $11.4 million decrease in personnel-related expenses [443]. - G&A expenses decreased by 9% to $71.9 million for the year ended December 31, 2024, from $78.7 million in 2023, mainly due to a $4.6 million decrease in personnel-related expenses and a $3.3 million decrease in subsidiary-related expenses [444]. - Non-operating income increased to $5.8 million for the year ended December 31, 2024, from $37,000 in 2023, primarily due to a $5.3 million gain on early lease terminations [446]. - Interest expense, net increased to $117.6 million for the year ended December 31, 2024, from $97.9 million in 2023, mainly due to increased non-cash interest related to the Royalty Purchase Agreement [447]. - The accumulated deficit reached $2.18 billion as of December 31, 2024, with significant losses expected to continue over the next several years [457]. - Cash, cash equivalents, and short-term investments decreased to $40.4 million as of December 31, 2024, down $35.7 million from the previous year [459]. - Net cash used in operating activities was $158.3 million for the year ended December 31, 2024, compared to $224.2 million in 2023 [465]. Debt and Financing - Long-term debt amounts to $37.459 billion, with $3.660 billion due in less than 1 year and $33.799 billion due in 1-3 years [467]. - The company raised approximately $2.01 billion through various financing activities since inception, including common and preferred stock sales [457]. - The company is in discussions for funding to support operations through the planned registration and launch strategy for its product candidates [462]. Clinical Development and Collaborations - The lead program, BOT, received Fast Track designation from the FDA in April 2023 for treating non-MSI-H and/or dMMR metastatic colorectal cancer [422]. - The company has established collaborations with several firms, including BMS, Gilead, and Merck, resulting in over a dozen antibody pre-clinical or clinical development programs [423]. - In 2024, Merck limited further clinical development of MK-4830 to a neoadjuvant ovarian study in combination with pembrolizumab and chemotherapy [426]. - The company is eligible to receive up to approximately $136.3 million and $49.4 million in potential development, regulatory, and commercial milestones from UroGen and Merck, respectively [432]. - MiNK Pharmaceuticals, a subsidiary, completed its IPO in October 2021 and is focused on developing allogeneic iNKT cell therapies, with a Phase 2 trial for agenT-797 actively enrolling [436]. - The company has entered into a Purchase and Sale Agreement with Ligand Pharmaceuticals, selling a portion of future milestone payments and royalties from various collaborations [432]. - The company aims to advance innovation in vaccine adjuvant discovery through its subsidiary SaponiQx, focusing on saponin-based adjuvants [433]. Operational and Investment Policies - Total payments estimated for third-party agreements related to clinical studies are projected to be $660.7 million, with $616.5 million expensed through December 31, 2024 [464]. - Cash and cash equivalents as of December 31, 2024, stand at $40.4 million, exposed to interest and foreign currency exchange rate changes [477]. - Approximately 2.1% of cash used in operations for the year ended December 31, 2024, was from foreign subsidiaries, indicating exposure to foreign currency exchange rate fluctuations [476]. - The company does not currently employ specific strategies to manage foreign currency exchange rate risks, such as derivatives or hedging [476]. - The investment policy aims to preserve principal, maintain liquidity, and maximize yields, prohibiting investments in structured vehicles and asset-backed commercial paper [478]. - Non-cash interest expense related to royalty financing transactions is recorded based on estimated royalty payments, which may vary due to several factors [473]. - The company is exposed to fluctuations in interest rates as it seeks debt financing and invests excess cash [477]. - The company periodically reviews and amends its investment policy as necessary to mitigate credit risk [478]. - The company has identified critical accounting policies that require complex judgments and estimates, which may differ from actual results [469].

Agenus Inc. (NASDAQ:AGEN) Q4 2024 Earnings Conference Call March 11, 2025 8:30 AM ET Company Participants Zack Armen - Head of Investor Relations, Corporate Development Garo Armen - Chairman and Chief Executive Officer Christine Klaskin - Vice President, Finance and Principal Financial and Accounting Officer Steven O'Day - Chief Medical Officer Robin Taylor - Chief Commercial Officer Conference Call Participants Emily Bodnar - H.C. Wainwright Mayank Mamtani - B. Riley Securities Operator Good morning and we ...

Agenus (AGEN) came out with a quarterly loss of $2.04 per share versus the Zacks Consensus Estimate of a loss of $2.36. This compares to loss of $2.60 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of 13.56%. A quarter ago, it was expected that this biotechnology company would post a loss of $2.10 per share when it actually produced a loss of $3.17, delivering a surprise of -50.95%.Over the last four quarters, the company has su ...

Financial Performance - Agenus Inc. reported financial results for Q4 and the year ended December 31, 2024[6] - The company issued a press release on March 11, 2025, detailing its financial performance[6] - Specific financial metrics and user data were not provided in the available content[6]

Group 1 - Momentum investing contrasts with the traditional "buy low and sell high" strategy, focusing instead on "buying high and selling higher" to capitalize on fast-moving stocks [1] - Identifying the right entry point for trending stocks can be challenging, as they may lose momentum if future growth does not justify their high valuations [1] - A safer investment approach involves targeting bargain stocks that exhibit recent price momentum, utilizing tools like the Zacks Momentum Style Score [2] Group 2 - Agenus (AGEN) is highlighted as a strong candidate for investment, showing a four-week price change of 14.7%, indicating growing investor interest [3] - AGEN has demonstrated significant long-term momentum, with a 28.7% price increase over the past 12 weeks and a beta of 1.31, suggesting it moves 31% more than the market [4] - The stock has a Momentum Score of B, indicating a favorable time for investment to leverage its momentum [5] Group 3 - AGEN's upward trend in earnings estimate revisions has contributed to its Zacks Rank 2 (Buy), which is associated with strong momentum effects [6] - The stock is currently trading at a Price-to-Sales ratio of 0.57, indicating it is undervalued at 57 cents for each dollar of sales [6] - AGEN is positioned for further growth, with potential for fast-paced performance [7]

Company Performance - Agenus (AGEN) has returned approximately 27.7% year-to-date, significantly outperforming the average return of 5.6% for the Medical sector [4] - The Zacks Consensus Estimate for Agenus's full-year earnings has increased by 33.3% over the past three months, indicating improved analyst sentiment and a more positive earnings outlook [3] Industry Comparison - Agenus is part of the Medical - Biomedical and Genetics industry, which includes 512 stocks and currently ranks 73 in the Zacks Industry Rank. This industry has gained about 5% year-to-date, showing that Agenus is performing better than its peers [5] - In contrast, another Medical stock, Concentra Group (CON), has returned 18.8% year-to-date and belongs to the Medical Services industry, which is ranked 178 and has moved up by 2% this year [4][6] Zacks Rank - Agenus holds a Zacks Rank of 2 (Buy), which is indicative of its potential to outperform the market in the near term [3] - The Zacks Rank system emphasizes earnings estimates and revisions, highlighting stocks that are likely to beat the market over the next one to three months [3]

Core Viewpoint - Agenus (AGEN) has received an upgrade to a Zacks Rank 2 (Buy) due to an upward trend in earnings estimates, which is a significant factor influencing stock prices [1][3]. Earnings Estimates and Stock Price Movement - The Zacks rating system is based on the Zacks Consensus Estimate, which reflects EPS estimates from sell-side analysts for the current and following years [1][2]. - Changes in a company's future earnings potential, as indicated by earnings estimate revisions, are strongly correlated with near-term stock price movements [4][6]. - Rising earnings estimates for Agenus indicate an improvement in the company's underlying business, which is expected to drive the stock price higher [5][10]. Zacks Rank System - The Zacks Rank stock-rating system classifies stocks into five groups based on earnings estimates, with Zacks Rank 1 (Strong Buy) to Zacks Rank 5 (Strong Sell) [7]. - Historically, Zacks Rank 1 stocks have generated an average annual return of +25% since 1988, demonstrating the effectiveness of the system [7]. Recent Performance of Agenus - For the fiscal year ending December 2024, Agenus is expected to earn -$12.84 per share, reflecting a year-over-year change of 7% [8]. - Over the past three months, the Zacks Consensus Estimate for Agenus has increased by 13.3%, indicating positive sentiment among analysts [8][10]. Conclusion - The upgrade of Agenus to a Zacks Rank 2 places it in the top 20% of Zacks-covered stocks based on estimate revisions, suggesting potential for market-beating returns in the near term [9][10].

For those looking to find strong Medical stocks, it is prudent to search for companies in the group that are outperforming their peers. Agenus (AGEN) is a stock that can certainly grab the attention of many investors, but do its recent returns compare favorably to the sector as a whole? Let's take a closer look at the stock's year-to-date performance to find out.Agenus is one of 1010 individual stocks in the Medical sector. Collectively, these companies sit at #1 in the Zacks Sector Rank. The Zacks Sector R ...

Core Viewpoint - Agenus (AGEN) has experienced significant selling pressure, resulting in a 41.6% decline in stock price over the past four weeks, but analysts anticipate improved earnings in the near future [1]. Group 1: Technical Analysis - The Relative Strength Index (RSI) for AGEN is currently at 16.18, indicating that the heavy selling may be exhausting, suggesting a potential rebound [5]. - AGEN's RSI reading of 32.579 as of November 8, 2023, indicates it is approaching oversold territory, which typically signals a possible price reversal [6]. Group 2: Earnings Estimates - There has been a strong consensus among sell-side analysts to raise earnings estimates for AGEN, leading to a 38.9% increase in the consensus EPS estimate over the last 30 days [7]. - An upward trend in earnings estimate revisions is generally associated with price appreciation in the near term [7]. Group 3: Analyst Ratings - AGEN currently holds a Zacks Rank 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks based on earnings estimate revisions and EPS surprises, indicating a potential turnaround [8].