We recently compiled a list of the 20 Best Biotech Stocks Under $20 to Buy Now. One of the best biotech stocks on our list is Altimmune, Inc. TheFly reported on January 27 that Barclays initiated coverage of ALT with an Overweight rating and a $20 price target. Strong underlying fundamentals, continuous merger and acquisition activity, and alleviating medication pricing concerns are the reasons behind the firm’s optimistic outlook for the biotech industry in 2026. Additionally, Barclays pointed out that A ...

Group 1 - Altimmune, Inc. has closed a registered direct offering of 17,045,454 shares, generating approximately $75 million in gross proceeds before fees and expenses [1][2] - The funds will be used for the upcoming Phase 3 trial in metabolic dysfunction-associated steatohepatitis (MASH) and for general corporate purposes [2] - The offering was facilitated by Titan Partners, acting as the sole placement agent [3] Group 2 - Pemvidutide, Altimmune's lead candidate, is a dual-action therapy targeting glucagon and GLP-1 receptors, showing potential as a differentiated treatment for MASH [2][6] - The company has received Breakthrough Therapy Designation from the U.S. FDA for pemvidutide, indicating its significance in addressing serious liver diseases [2] - Altimmune is focused on delivering long-term value for shareholders while enhancing its operational flexibility through this investment [2]

Core Viewpoint - Altimmune Inc has announced a $75 million registered direct offering of common stock, leading to a significant decline in its share price [1][9]. Group 1: Offering Details - The company has entered a securities purchase agreement for the sale of 17,045,454 shares of common stock, or pre-funded warrants [2]. - The offering is expected to generate approximately $75 million in gross proceeds, priced at about $4.40 per share, and is anticipated to close around January 29, subject to customary conditions [3]. Group 2: Use of Proceeds - Net proceeds from the offering will be used to fund preparations for the upcoming Phase 3 trial in metabolic dysfunction-associated steatohepatitis (MASH), along with working capital and general corporate purposes [4]. Group 3: Stock Performance - Currently, Altimmune's stock is trading 17.4% above its 20-day simple moving average and 19.8% above its 100-day simple moving average, indicating short-term strength despite the recent decline [5]. - Over the past 12 months, shares have decreased by approximately 26.33% and are closer to their 52-week lows than highs [5]. - The stock's RSI is at 78.59, indicating overbought territory, while the MACD shows bullish momentum, suggesting a potential correction may be due [6]. Group 4: Company Overview - Altimmune is a clinical-stage biopharmaceutical company focused on developing treatments for obesity, metabolic diseases, and liver diseases, with its product candidate pemvidutide being a dual receptor agonist currently in clinical development [7]. - The recent stock offering is significant as it aims to fund further development of pemvidutide, which could address major health issues [8].

Core Insights - Premarket trading is showing notable activity with significant price movements indicating potential trading opportunities before the market opens [1] Premarket Gainers - Murano Global Investments Plc (MRNO) is up 146% at $3.35 [3] - Kustom Entertainment, Inc. (KUST) is up 34% at $2.84 [3] - Ainos, Inc. (AIMD) is up 34% at $2.32 [3] - Stride, Inc. (LRN) is up 29% at $94.10 [3] - Shuttle Pharmaceuticals Holdings, Inc. (SHPH) is up 18% at $2.40 [3] - Battalion Oil Corporation (BATL) is up 16% at $3.83 [3] - C3.ai, Inc. (AI) is up 15% at $14.58 [3] - Lantronix, Inc. (LTRX) is up 14% at $7.87 [3] - Nextpower Inc. (NXT) is up 13% at $120.00 [3] - High Roller Technologies, Inc. (ROLR) is up 7% at $7.56 [3] Premarket Losers - Flora Growth Corp. (FLGC) is down 34% at $7.20 [4] - TEN Holdings, Inc. (XHLD) is down 29% at $2.47 [4] - Global Interactive Technologies, Inc. (GITS) is down 22% at $3.25 [4] - 5E Advanced Materials, Inc. (FEAM) is down 15% at $2.70 [4] - Vyome Holdings, Inc. (HIND) is down 14% at $2.79 [4] - Altimmune, Inc. (ALT) is down 11% at $5.48 [4] - BiomX Inc. (PHGE) is down 10% at $6.22 [4] - Qorvo, Inc. (QRVO) is down 9% at $74.94 [4] - Nuwellis, Inc. (NUWE) is down 9% at $3.45 [4] - Brenmiller Energy Ltd (BNRG) is down 9% at $2.90 [4]

Core Viewpoint - Altimmune, Inc. has entered into a securities purchase agreement for the sale of 17,045,454 shares of common stock, expected to generate approximately $75 million in gross proceeds, to fund its Phase 3 trial for pemvidutide and for general corporate purposes [1][2]. Group 1: Offering Details - The offering involves 17,045,454 shares of common stock or pre-funded warrants, with gross proceeds anticipated to be around $75 million before expenses [1]. - The offering is expected to close on or about January 29, 2026, pending customary closing conditions [1]. - Titan Partners is acting as the sole placement agent for this offering [3]. Group 2: Use of Proceeds - The net proceeds from the offering will be utilized to prepare for the upcoming Phase 3 trial in metabolic dysfunction-associated steatohepatitis (MASH), along with working capital and general corporate purposes [2]. - Pemvidutide is a dual agonist targeting glucagon and GLP-1 receptors, showing potential as a differentiated therapy for MASH, supported by recent Phase 2b data and Breakthrough Therapy Designation from the U.S. FDA [2]. Group 3: Company Overview - Altimmune is a late clinical-stage biopharmaceutical company focused on therapies for serious liver diseases, with pemvidutide as its lead candidate [6]. - The company aims to deliver significant patient impact and long-term shareholder value through its innovative therapies [2].

Core Insights - Shares of Altimmune (NASDAQ: ALT) experienced a significant increase of 35.4% over the past week, indicating a strong positive shift in retail investor sentiment [1] Company Summary - The surge in Altimmune's stock price coincided with a notable change in retail investor behavior on platforms like Reddit, suggesting a potential influence of social media on investment decisions [1]

Core Insights - ALT5 Sigma Corporation, a fintech company, reported its financial results for the fiscal quarter ending September 27, 2025, highlighting significant financial, strategic, and operational milestones achieved during the quarter [1]. Financial Performance - The company maintains a strategic digital asset treasury valued at $WLFI, which is integral to its operations [1]. - The financial results indicate meaningful progress in the company's blockchain-powered payment and trading infrastructure for digital assets [1]. Strategic Developments - ALT5 Sigma Corporation is focused on enhancing its card-based payment programs, which are part of its broader strategy to leverage digital assets [1]. - The company has made notable advancements in its operational capabilities, reflecting its commitment to growth in the fintech sector [1].

Core Insights - Altimmune (ALT) has received FDA Breakthrough Therapy Designation for pemvidutide, a dual receptor agonist aimed at treating metabolic dysfunction-associated steatohepatitis (MASH) [1][5] - The Breakthrough Therapy designation is designed to expedite the development and review of therapies for serious diseases with unmet medical needs [2] - Following the announcement, ALT's shares increased by 16.52%, although they have seen a 44% decline over the past year compared to a 1.4% rise in the industry [2] Study Data - The Breakthrough Therapy status is supported by 24-week data from the phase IIb IMPACT study, which showed significant MASH resolution without worsening fibrosis and early improvements in liver health markers [3][5] - In December, 48-week data from the IMPACT study indicated continued significant improvements in liver health markers and weight loss at the 1.8 mg dose [6] - Altimmune confirmed alignment with the FDA to advance pemvidutide into a phase III study for MASH patients with moderate to severe liver fibrosis, expected to begin in 2026 [7] Additional Developments - Pemvidutide is also being developed for alcohol use disorder (AUD) and alcohol-associated liver disease (ALD) in mid-stage studies, with Fast Track designations already granted for MASH and AUD [8]

Core Insights - Altimmune, Inc. has received Breakthrough Therapy Designation from the FDA for its drug pemvidutide, indicating significant potential for improvement over existing therapies for serious liver diseases [2][6] - The company reported promising 48-week Phase IIb data for pemvidutide, showing durable improvements in non-invasive fibrosis markers and a weight loss of 7.5% at a 1.8 mg dose, supporting progression to Phase III trials [3][6] - Altimmune is optimistic about regulatory alignment for a Phase III trial, which will focus on biopsy-based endpoints and test a 2.4 mg dose [4][6] Stock Performance - The stock price of Altimmune is currently at $4.09, reflecting a significant increase of 16.52% with a change of $0.58, indicating investor confidence [4] - Over the past year, the stock has fluctuated between a low of $2.90 and a high of $7.83, with a current market capitalization of approximately $361 million and a trading volume of 26.77 million shares [5]

Market Overview - U.S. stocks experienced an upward trend, with the Dow Jones index increasing by over 500 points on Monday [1] Company Highlights - Altimmune Inc (NASDAQ:ALT) saw a significant increase of 23.6%, reaching $4.34, following the FDA's grant of Breakthrough Therapy Designation for Pemvidutide in MASH [1] - GH Research PLC (NASDAQ:GHRS) surged by 33.8% to $17.72 after the FDA lifted the clinical hold on its Investigational New Drug Application for GH001 [2] - Vicor Corp (NASDAQ:VICR) rose by 20.7% to $141.08 [2] - Critical Metals Corp (NASDAQ:CRML) increased by 19.6% to $9.71 [2] - Kosmos Energy Ltd (NYSE:KOS) gained 19.3% to $1.06 after issuing an operational and financial update [2] - TRON Inc (NASDAQ:TRON) increased by 16.9% to $1.59 [2] - Nuscale Power Corp (NYSE:SMR) rose by 15.7% to $18.88 [2] - Regencell Bioscience Holdings Ltd (NASDAQ:RGC) increased by 15.4% to $23.71 [2] - Rayonier Advanced Materials Inc (NYSE:RYAM) gained 14.1% to $6.68, with the appointment of Scott M. Sutton as President and CEO [2] - Aduro Clean Technologies Inc (NASDAQ:ADUR) rose by 14% to $12.05 [2] - Gyre Therapeutics Inc (NASDAQ:GYRE) increased by 12.7% to $7.67, announcing alignment with China's CDE on conditional approval pathway for hydronidone [2] - Endeavour Silver Corp (NYSE:EXK) gained 12.5% to $10.16 [2] - Allegro MicroSystems Inc (NASDAQ:ALGM) surged by 11.9% to $30.12 [2] - United States Antimony Corp (NYSE:UAMY) rose by 11.7% to $6.69 [2] - Oklo Inc (NYSE:OKLO) gained 11.5% to $86.82 [2] - Figure Technology Solutions Inc (NASDAQ:FIGR) increased by 11.3% to $48.66 [2] - Valero Energy Corp (NYSE:VLO) rose by 9.6% to $181.21 [2] - AeroVironment, Inc. (NASDAQ:AVAV) increased by 8.6% to $278.31 [2] - Coeur Mining Inc (NYSE:CDE) gained 8.5% to $19.05 [2] - Halliburton Co (NYSE:HAL) rose by 7.8% to $31.92, with U.S. energy stocks trading higher amid news of potential investments in Venezuela's oil industry [2] - Kratos Defense & Security Solutions Inc (NASDAQ:KTOS) gained 7.7% to $85.39 [2] - Slb NV (NYSE:SLB) increased by 7.4% to $43.19 [2] - Amkor Technology Inc (NASDAQ:AMKR) rose by 7.3% to $46.05, with Needham analyst Charles Shi maintaining a Buy rating and raising the price target from $37 to $50 [2]