Heron Therapeutics, Inc. (NASDAQ:HRTX) Q4 2024 Earnings Conference Call February 27, 2025 8:00 AM ET Company Participants Melissa Jarel - Executive Director, Legal Craig Collard - Chief Executive Officer Ira Duarte - Executive Vice President, Chief Financial Officer Bill Forbes - Executive Vice President, Chief Development Officer Kevin Warner - Senior Vice President, Medical Affairs, Strategy and Engagement Conference Call Participants Brandon Folkes - Rodman & Renshaw Serge Belanger - Needham Carl Byrnes ...

Heron Therapeutics (HRTX) reported $40.78 million in revenue for the quarter ended December 2024, representing a year-over-year increase of 19.1%. EPS of $0.02 for the same period compares to -$0.07 a year ago.The reported revenue compares to the Zacks Consensus Estimate of $36.95 million, representing a surprise of +10.37%. The company delivered an EPS surprise of +166.67%, with the consensus EPS estimate being -$0.03.While investors closely watch year-over-year changes in headline numbers -- revenue and e ...

Revenue and Sales Performance - The company reported net product sales from ZYNRELEF, APONVIE, CINVANTI, and SUSTOL, with revenues dependent on various factors including market conditions and customer agreements [306]. - Net product sales for 2024 reached $144.3 million, a 13.6% increase from $127.0 million in 2023 [331]. - Acute care net product sales grew by 57.3% in 2024, driven by increased market share and the commercial launch of APONVIE in March 2023 [331]. - Total acute care net product sales increased by 87.5% in 2023 compared to 2022, indicating strong growth momentum [332]. Expenses and Cost Management - Research and development expenses primarily consist of salaries, stock-based compensation, and costs related to clinical and preclinical development, with all costs expensed in the period incurred [308]. - General and administrative expenses include salaries and related costs for various personnel functions, as well as professional fees for legal and corporate purposes [309]. - Sales and marketing expenses are focused on personnel costs and commercialization efforts related to the company's products [310]. - Research and development expenses decreased by 57.4% in 2024 to $16.7 million, primarily due to restructuring and reduced headcount [337]. - Operating expenses as a percentage of sales decreased across all categories in 2024, with sales and marketing expenses down 30.4% [341]. - Cost of product sales decreased by 40.6% in 2024, primarily due to reduced inventory reserves and improved production efficiency [334]. Financial Position and Cash Management - Cash, cash equivalents, and short-term investments totaled $59.3 million as of December 31, 2024, sufficient to meet anticipated cash requirements for at least one year [345]. - The company has $175.5 million in current indebtedness that will need to be refinanced to fully fund its business plan [345]. - The company invests in marketable securities to preserve capital, maintain liquidity, and maximize yields, with a focus on high credit quality financial institutions [357]. - The investment portfolio includes only marketable securities and instruments with active secondary markets to ensure liquidity [357]. - The company does not expect material impact on operating results from sudden interest rate changes, as it can hold fixed-income investments to maturity [357]. Risks and Economic Factors - The company faces significant risks from global business, political, and macroeconomic conditions, including financial market volatility and potential government shutdowns [304]. - Foreign currency exposure is primarily to fluctuations in the Euro, but the company does not anticipate significant transaction gains or losses at current operational levels [358]. - The company has not engaged in foreign currency hedging to date, and any gains or losses are included in the Consolidated Statements of Operations [358]. - Inflation has not materially impacted the company's business or results of operations during the reporting periods [359]. - Significant adverse changes in inflation could negatively impact future results of operations [359]. Profitability and Loss - The company reported a net loss of $13.6 million in 2024, a significant reduction from a net loss of $110.6 million in 2023 [346]. - Gross profit for 2024 was $105.6 million, significantly up from $61.9 million in 2023, reflecting improved cost management [330]. Revenue Recognition and Inventory Management - Revenue recognition follows the Financial Accounting Standards Board guidelines, ensuring that revenue reflects the transfer of goods or services to customers [316]. - The company monitors inventory levels and may write down obsolete inventory or inventory exceeding expected sales requirements [323]. - Stock-based compensation is estimated using the Black-Scholes model, with assumptions that could impact net loss and net loss per share if changed [327]. Agreements and Collaborations - A five-year co-promotion agreement was established with Crosslink Network to enhance the promotion of ZYNRELEF for orthopedic indications, with compensation based on growth over a predetermined baseline [305].

Heron Therapeutics Announces Fourth Quarter and Full-Year 2024 Financial Results and Highlights Recent Corporate Updates "2024 was a milestone year for Heron. We delivered strong financial results, including positive Net Income for Q4 2024, achieved our operational objectives, and repositioned the business for future growth. As we move into 2025, our product ZYNRELEF is poised for transformational growth, driven by its expanded label indications, the launch of the VAN, the approval of the NOPAIN Act, and th ...

Achieved Q4 2024 GAAP Net Income of $3.6 million Generated full-year 2024 Net Revenue of $144.2 million, up 14% year-over-year Delivered full-year 2024 adjusted EBITDA of $8.6 million Generated ZYNRELEF® Q4 2024 Net Revenue of $8.5 million and launched the ZYNRELEF Vial Access Needle ("VAN") in December 2024 U.S. District Court ruled in favor of Heron in patent lawsuit against Fresenius Kabi USA, LLC, and upheld the validity of CINVANTI® patents which expire in 2035 CARY, N.C., Feb. 27, 2025 /PRNewswire/ - ...

Core Viewpoint - Heron Therapeutics, Inc. will host a conference call and live webcast on February 27, 2025, to report its fourth quarter and full year 2024 financial results and discuss recent business highlights [1]. Company Overview - Heron Therapeutics, Inc. is a commercial-stage biotechnology company focused on developing and commercializing therapeutic innovations aimed at improving medical care for patients [3]. - The company utilizes advanced science, patented technologies, and an innovative approach to drug discovery and development to create a portfolio of products that enhance the standard-of-care for acute care and oncology patients [3]. Conference Call Details - The conference call can be accessed via a registration link that provides dial-in details, and participants are encouraged to join fifteen minutes early to avoid delays [2]. - The call will also be available through a webcast on Heron's website, with an archive accessible for 60 days following the event [2].

SAN DIEGO, Dec. 23, 2024 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX) ("Heron" or the "Company"), a commercial-stage biotechnology company, announced today the relocation of the Company's headquarters from San Diego, California to Cary, North Carolina, effective January 1, 2025. A majority of Heron's Management Team and corporate employees work from the Cary office, which is near the Research Triangle Park ("RTP"), one of the most prominent high-tech research and development parks in the United S ...

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— Court Rules in Favor of Heron in Patent Lawsuit Against Fresenius Kabi USA, LLC —SAN DIEGO, Dec. 3, 2024 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX) ("Heron" or the "Company"), a commercial-stage biotechnology company, today announced that the U.S. District Court for the District of Delaware ruled in Heron's favor in the Company's patent litigation against Fresenius Kabi USA, LLC with respect to CINVANTI® (aprepitant) injectable emulsion. The district court found that Heron's U.S. Patent Nos. ...

Heron Therapeutics, Inc. (NASDAQ:HRTX) Q3 2024 Earnings Conference Call November 12, 2024 8:00 AM ET Company Participants Melissa Jarel - Executive Director Craig Collard - Chief Executive Officer Ira Duarte - Executive Vice President & Chief Financial Officer William Forbes - Executive Vice President & Chief Development Officer Conference Call Participants Carl Byrnes - Northland Capital Markets Serge Belanger - Needham Brandon Folkes - Rodman & Renshaw Operator Thank you for standing by and welcome to Her ...