Exhibit 99.1 FOR IMMEDIATE RELEASE Incyte Reports 2024 Fourth Quarter and Year-End Financial Results, Provides 2025 Financial Guidance and Highlights 2025 R&D Milestones Conference Call and Webcast Scheduled Today at 8:00 a.m. ET WILMINGTON, Del. – February 10, 2025 – Incyte (Nasdaq:INCY) today announced financial results for the fourth quarter and full year ended December 31, 2024 and provided full year 2025 financial guidance. "2024 was an important year for Incyte, with a 15% increase in total revenues, ...

Core Viewpoint - Incyte (INCY) is expected to report strong quarterly earnings with a projected EPS of $1.58, reflecting a 49.1% increase year-over-year, and revenues forecasted at $1.15 billion, indicating a 13.5% increase compared to the same period last year [1]. Earnings Projections - The consensus EPS estimate has been revised upward by 3.2% in the last 30 days, indicating a reassessment by analysts [2]. - Changes in earnings projections are crucial for predicting investor reactions, with empirical studies showing a strong correlation between earnings estimate trends and short-term stock price movements [3]. Revenue Estimates - Analysts project 'Revenues- Product royalty revenues' to be $161.69 million, reflecting an 8.1% increase year-over-year [5]. - 'Net product revenues- Iclusig' are expected to reach $29.69 million, indicating a 9.4% year-over-year change [5]. - 'Revenues- Product revenues' are forecasted at $979.15 million, representing a 13.6% increase from the prior year [5]. Specific Product Revenue Forecasts - 'Net product revenues- Pemazyre' are estimated at $22.54 million, showing a 9.1% increase year-over-year [6]. - 'Net product revenues- Minjuvi/ Monjuvi' are projected at $33.75 million, reflecting a significant increase of 275.2% from the previous year [6]. - 'Net product revenues- Opzelura' are expected to be $147.91 million, indicating a 35.4% increase year-over-year [6]. - 'Net product revenues- Jakafi' are projected to reach $744.96 million, reflecting a 7.2% increase [7]. - 'Royalty revenues- Olumiant' are expected to be $39.58 million, indicating a slight decrease of 1.9% [7]. - 'Royalty revenues- Tabrecta' are forecasted at $6.27 million, reflecting a 34.1% increase [7]. - 'Royalty revenues- Jakavi' are estimated at $116.30 million, indicating an 11.9% increase year-over-year [8]. Stock Performance - Over the past month, Incyte shares have recorded a return of +1.3%, compared to the Zacks S&P 500 composite's +1.7% change, suggesting that INCY is likely to perform in line with the overall market [9].

Incyte Corporation (INCY) is scheduled to report fourth-quarter and full-year 2024 results on Feb. 10, before the opening bell. The Zacks Consensus Estimate for the to-be-reported quarter’s revenues is pegged at $1.15 billion, while the same for earnings is pinned at $1.58 per share.Find the latest EPS estimates and surprises on Zacks Earnings Calendar.In the past year, shares of Incyte have rallied 27.1% against the industry’s decline of 9.9%.Image Source: Zacks Investment ResearchLet’s see how things migh ...

Shares of Incyte (INCY) have risen 15.3% in the past twelve months against the industry’s decline of 14.3%. The stock has outperformed the sector but lagged S&P 500 during this time frame.The outperformance can be attributed to new drug approvals and recent pipeline progress. Lead drug Jakafi (ruxolitinib) also maintains momentum.At the recently held J.P. Morgan Healthcare Conference, management highlighted that 2025 will be a transformational year for INCY with four potential launches.INCY Outperforms Indu ...

Niktimvo Approval and Launch - Niktimvo, a first-in-class therapeutic agent, was approved by the FDA on August 14, 2024, for the treatment of chronic GVHD after failure of at least two prior lines of systemic therapy [1][26] - The approval was based on positive data from the global AGAVE-201 trial, which showed 75% of patients receiving 0.3 mg/kg every two weeks achieved a response at six months of treatment (N=79) [1] - Niktimvo is the first and only FDA-approved anti-CSF-1R antibody targeting the drivers of inflammation and fibrosis in chronic GVHD [3][26] - The U.S. launch of Niktimvo is expected in early February 2025, with product available in 9 mg and 22 mg vial sizes [26] Chronic GVHD and Market Need - Chronic GVHD is a serious condition affecting approximately 17,000 patients in the U.S., with nearly 50% of patients requiring at least three lines of treatment [5] - The condition develops in approximately 42% of allogeneic stem cell transplant recipients, highlighting the significant unmet medical need [5] AGAVE-201 Trial Results - The AGAVE-201 trial evaluated axatilimab in 241 patients with recurrent or refractory chronic GVHD, showing durable responses across all organs studied and patient subgroups [6][26] - The trial's primary endpoint was the proportion of patients achieving an objective response by cycle 7 day 1, with secondary endpoints including duration of response and quality-of-life assessments [6] Commercialization and Partnerships - Incyte and Syndax are co-commercializing Niktimvo in the U.S., with Incyte holding exclusive commercialization rights outside the U.S. [29] - Syndax licensed exclusive worldwide rights to develop and commercialize axatilimab from UCB in 2016, and entered into a co-development and co-commercialization agreement with Incyte in September 2021 [9] Pipeline and Future Development - Axatilimab is being studied in frontline combination trials for chronic GVHD, including a Phase 2 trial with ruxolitinib and a Phase 3 trial with steroids [10] - Additional studies are underway for idiopathic pulmonary fibrosis, indicating potential expansion of axatilimab's therapeutic applications [10] Patient Support and Access - IncyteCARES provides personalized patient support, including financial assistance and education, to eligible U.S. patients prescribed Niktimvo [4]

For those looking to find strong Medical stocks, it is prudent to search for companies in the group that are outperforming their peers. Has Incyte (INCY) been one of those stocks this year? By taking a look at the stock's year-to-date performance in comparison to its Medical peers, we might be able to answer that question.Incyte is one of 1011 individual stocks in the Medical sector. Collectively, these companies sit at #1 in the Zacks Sector Rank. The Zacks Sector Rank includes 16 different groups and is l ...

Professional Background - Brendan completed a Ph.D. in organic synthesis at Stanford University in 2009 [1] - Worked at Merck, a major pharmaceutical company, from 2009 to 2013 [1] - Gained experience in biotech startups, including Theravance and Aspira, before joining Caltech [1] - Co-founded 1200 Pharma as its first employee, securing significant investment (8 figures) when it spun out of Caltech [1] Investment Focus - Remains an active investor with a focus on market trends, particularly in biotechnology stocks [1] Note: The content does not provide specific company or industry analysis, financial data, or investment opportunities, as it primarily focuses on an individual's professional background and investment interests. The disclosure and risk-related sections have been excluded as per the task instructions.

Investors interested in Medical - Biomedical and Genetics stocks are likely familiar with Incyte (INCY) and Vertex Pharmaceuticals (VRTX) . But which of these two stocks presents investors with the better value opportunity right now? Let's take a closer look.The best way to find great value stocks is to pair a strong Zacks Rank with an impressive grade in the Value category of our Style Scores system. The proven Zacks Rank puts an emphasis on earnings estimates and estimate revisions, while our Style Scores ...

Most recently in the ever-growing biotech industry, investors are musing over potential changes to the sector after President-elect Donald Trump picked Martin “Marty” Makary to be the U.S. Food and Drug Administration's (FDA) next commissioner, and Robert F. Kennedy Jr. to lead the Department of Health and Human Services. Today, we'll check checking in with three heavy-hitting biotech stocks and how they've been faring on the charts. Regeneron Pharmaceuticals Inc (NASDAQ:REGN) stock is finally on the reboun ...

Core Viewpoint - Incyte's recent earnings report showed mixed results, with adjusted earnings missing estimates but total revenues exceeding expectations, driven by strong sales of its lead drug Jakafi and the newly launched Opzelura cream [2][3]. Financial Performance - Adjusted earnings for Q3 2024 were $1.07 per share, missing the Zacks Consensus Estimate of $1.12, and down from $1.10 per share in the same quarter last year [2]. - Total revenues reached $1.14 billion, reflecting a year-over-year growth of 23.8%, surpassing the Zacks Consensus Estimate of $1.09 billion [3]. Product Sales Breakdown - Jakafi generated revenues of $741.2 million, a 16% increase from the previous year, driven by a 10% rise in total demand, and exceeded the Zacks Consensus Estimate of $717.5 million [4]. - Opzelura cream sales amounted to $139.3 million, up 52% year over year, surpassing the Zacks Consensus Estimate of $130.8 million, attributed to growth in new patient starts and refills [5]. - Zynyz, a newly approved drug, generated $0.69 million in sales, while Iclusig and Pemazyre reported revenues of $29.7 million (up 7%) and $20.7 million (down 9%), respectively [6]. Royalty Revenues - Jakavi royalty revenues from Novartis increased by 20% to $115.7 million, beating the Zacks Consensus Estimate of $104.7 million [8]. - Royalty revenues from Tabrecta sales were $5.9 million, up 43% year over year [9]. - Olumiant's product royalty revenues totaled $34.8 million, a 17% increase, but missed the Zacks Consensus Estimate of $35.2 million [10]. Expenses and Guidance - Adjusted R&D expenses rose to $525.3 million, a 51% increase year over year, primarily due to a $100 million milestone payment [11]. - Adjusted selling, general, and administrative expenses were $277.3 million, up 15% from the prior year [12]. - Incyte raised its 2024 revenue guidance for Jakafi to a range of $2.74-$2.77 billion, and adjusted R&D expenses are now expected to be between $2.395-$2.435 billion [13]. Recent Developments - In August 2024, Incyte and Syndax Pharmaceuticals received FDA approval for axatilimab-csfr, branded as Niktimvo, for chronic graft-versus-host disease [14]. Market Position and Outlook - Incyte's stock has seen a downward trend in estimates, with a consensus estimate shift of -6.38% [15][16]. - The company holds a Zacks Rank 3 (Hold), indicating expectations for an in-line return in the coming months [18]. - Incyte operates within the Zacks Medical - Biomedical and Genetics industry, where competitor Alkermes has shown an 11.4% gain over the past month [19].