UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-36510 ZAFGEN, INC. (Exact name of registrant as specified in its charter) Delaware 20-3857670 (State or other jurisdiction of incorporation or organization) (IRS Employer I ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-36510 ZAFGEN, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organiza ...

Zafgen® Investor Overview March 2019 Forward-Looking Statement 2 These slides and the accompanying oral presentation contain forward-looking statements and information. The use of words such as "may," "might," "will," "should," "expect," "plan," "anticipate," "believe," "estimate," "project," "intend," "future," "potential," or "continue," and other similar expressions are intended to identify forward looking statements. For example, all statements we make regarding the initiation, timing, progress and resu ...

Zafgen, Inc. (ZFGN) Q4 2018 Earnings Conference Call March 11, 2019 4:30 PM ET Company Participants John Woolford - IR, Westwicke Partners Jeffrey Hatfield - CEO Patricia Allen - CFO Conference Call Participants Ted Tenthoff - Piper Jaffray Operator Good day, ladies and gentlemen, and welcome to Zafgen's Fourth Quarter and Full Year 2018 Financial Results and Update Conference Call. At this time, all participants are in a listen-only mode. Later, we will conduct a question-and-answer session and instruction ...