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Stock futures were rising Thursday as investors parsed through a batch of economic data that has been released in recent days, including a delayed U.S. monthly jobs report. ...

This Biotech Stock Is Jumping 25% After Getting an FDA Boost - Barron'sSkip to Main ContentThis copy is for your personal, non-commercial use only. Distribution and use of this material are governed by our Subscriber Agreement and by copyright law. For non-personal use or to order multiple copies, please contact Dow Jones Reprints at 1-800-843-0008 or visit www.djreprints.com.# This Biotech Stock Is Jumping 25% After Getting an FDA BoostBy [Adam Clark]ShareResize---ReprintsIn this article[NVCR]Novocure's Op ...

U.S. stock futures rose on Thursday following Wednesday's decline. Futures of major benchmark indices were higher after the strong January jobs report.On Wednesday, the Dow Jones index declined, slipping after a record-high close on Tuesday.Meanwhile, the 10-year Treasury bond yield stood at 4.175%, and the two-year bond yield was 3.502%. The CME Group’s FedWatch tool‘s projections show markets pricing a 94.1% likelihood of the Federal Reserve leaving the current interest rates unchanged in March.IndexPerfo ...

NovoCure Ltd (NASDAQ:NVCR) shares are trending on Thursday.Shares of the oncology company surged 29.52% to $13.60 in after-hours trading on Wednesday after the Food and Drug Administration approved Optune Pax for the treatment of locally advanced pancreatic cancer.First Approval In Three DecadesThe approval marks the first new treatment for locally advanced pancreatic cancer in nearly 30 years, according to the company’s announcement. Optune Pax, which is a portable therapeutic device that delivers Tumor Tr ...

The Swiss biopharmaceutical company's shares surged in after-hours trading after it said the FDA approved its Optune Pax product. ...

BAAR, Switzerland--(BUSINESS WIRE)--Novocure (NASDAQ: NVCR) announced today that the U.S. Food and Drug Administration (FDA) approved Optune Pax® for the treatment of adult patients with locally advanced pancreatic cancer concomitant with gemcitabine and nab-paclitaxel. "In the Phase 3 PANOVA-3 trial, treatment with Optune Pax resulted in a statistically significant improvement in overall survival without adding to the systemic side effects commonly associated with existing therapies. It also s. ...

Company Overview - NovoCure has developed, pioneered, and commercialized an effective wearable cancer therapy that is currently a standard of care [4] Leadership and Strategy - Frank Leonard, the new CEO with over 15 years at the company, emphasizes a focus on driving growth through a reorganization of the commercial organization [2][3] - The company is looking ahead to a catalyst-rich year in 2026, indicating multiple upcoming developments that could impact its growth trajectory [2][3]

Summary of Novocure's Conference Call Company Overview - **Company**: Novocure - **Industry**: Biotech, specifically focused on cancer treatment - **Core Product**: Tumor Treating Fields (TTFields), a wearable cancer therapy primarily for glioblastoma patients [3][4] Key Points and Arguments Financial Performance - **2025 Preliminary Results**: Novocure reported $655 million in revenue, reflecting an 8% year-over-year growth [11] - **Growth in Active Patients**: A 9% increase in active patient volume globally, with notable growth in Japan (29%), France (19%), and Germany (10%) [12][13] - **Path to Profitability**: Commitment to reaching Adjusted EBITDA break-even, with plans to provide guidance on revenue and EBITDA in the upcoming earnings call [28] Product Development and Clinical Trials - **Clinical Success**: Demonstrated a five-month improvement in median overall survival for glioblastoma patients using TTFields, with a five-year survival rate exceeding 13% for consistent users [6] - **LUNAR Study**: Showed significant improvement in overall survival for non-small cell lung cancer patients when TTFields were used alongside systemic therapy [7] - **PANOVA-3 Study**: Reported a two-month overall survival benefit and a six-month extension in pain-free survival for pancreatic cancer patients [8][9] - **METIS Study**: Showed a doubling of time to intracranial progression when TTFields were added to stereotactic radiosurgery [10] Market Expansion and New Indications - **New Markets**: Plans to expand into pancreatic cancer and brain metastases from non-small cell lung cancer, with anticipated launches in 2026 [4][17][18] - **Total Addressable Market**: Estimated 15,000 patients for pancreatic cancer and 16,000 for brain metastases in the U.S. [17][18] R&D Focus - **Ongoing Studies**: Upcoming results from PANOVA-4 and TRIDENT studies, focusing on metastatic pancreatic cancer and newly diagnosed glioblastoma, respectively [21][22] - **Prioritization**: Focus on GBM and new indications while managing R&D investments to ensure a path to profitability [40] Challenges and Solutions - **Adoption Barriers**: Addressing patient burden related to skin sensitivity and device portability [41][42] - **Product Improvements**: Plans to introduce a new array to reduce skin irritation and redesign the device for better usability [42] Strategic Vision - **Long-term Goals**: Emphasis on tackling aggressive tumors with high unmet needs, while ensuring that the company remains focused on its core competencies [33][34] - **Commercial Strategy**: Aiming to drive adoption in existing markets while selectively expanding into new ones [27] Additional Important Content - **Unique Mechanism of Action**: TTFields utilize alternating electric fields to target cancer cells, which is distinct from traditional therapies [5] - **Patient-Centric Approach**: Commitment to enhancing patient experience through better technology and digital interaction [12] - **Legacy of Innovation**: Acknowledgment of the late Professor Yoram Palti, the founder of the technology, and the impact of TTFields on patient survival [29][30] This summary encapsulates the key insights from Novocure's conference call, highlighting the company's financial performance, product development, market strategies, and future growth opportunities.

Core Viewpoint - NovoCure Ltd. reported higher revenues for the fourth quarter and fiscal year 2025, indicating strong financial performance and growth potential for 2026 [1][2]. Financial Performance - Total preliminary net revenues for Q4 were $174.4 million, an increase of 8% from the same period last year [2]. - For fiscal 2025, total preliminary net revenues reached $655.4 million, also reflecting an 8% increase compared to the prior year [3]. - Revenue breakdown for Q4 included $101.6 million from the U.S., $21.6 million from Germany, $20.5 million from France, and $10.2 million from Japan, with an additional $15.8 million from other markets [2][3]. Future Outlook - The CEO stated that NovoCure is positioned for exciting growth opportunities in 2026, with plans for multiple product launches and a clear path to profitability [2]. - The company will cease reporting new prescriptions for indications that have been commercially available for over one year but will continue to report active patients segmented by product and market [3].