Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 _____________________________________________________________________________________________ Form 10-Q _____________________________________________________________________________________________ (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANG ...

Core Viewpoint - PacBio has entered a strategic collaboration with Chulalongkorn University to implement its HiFi whole genome sequencing technology in newborn screening, marking a significant advancement in genomic research and public health in the Asia Pacific region [1][4]. Company Summary - The collaboration represents the first population-scale deployment of PacBio's HiFi technology in the Asia Pacific, aimed at improving the identification of rare, treatable conditions in newborns [1][4]. - PacBio's HiFi WGS technology offers a more comprehensive view of the genome, capturing genetic variants that traditional methods may miss, thus enhancing early diagnosis and intervention capabilities [8][10]. - The company currently has a market capitalization of $336.1 million and anticipates earnings growth of 13.1% in 2025 [5]. Industry Summary - The global whole genome sequencing market is projected to reach $2.12 billion in 2024, with an expected compound annual growth rate (CAGR) of 22.17% from 2025 to 2030, driven by technological advancements and increasing demand for personalized medicine [11][12]. - The collaboration positions Thailand as a leader in precision medicine within the Asia Pacific, potentially catalyzing similar initiatives in other countries and expanding PacBio's market presence [10].

MENLO PARK, Calif., May 12, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) today announced that the Special Committee of its Board of Directors (the “Special Committee”) has concluded its independent investigation into previously disclosed allegations from an attorney representing an employee impacted by our recent reduction in force regarding certain employment practices and cybersecurity matters of the Company. The allegations did not involve the current, or any previously reported, financial results, and ...

Pacific Biosciences of California, Inc. (PACB) , popularly known as PacBio, delivered an adjusted loss per share of 15 cents in first-quarter 2025, narrower than the year-ago adjusted loss of 26 cents per share. The adjusted loss per share topped the Zacks Consensus Estimate by 21.1%. (Find the latest EPS estimates and surprises on Zacks Earnings Calendar.)The company’s GAAP loss per share was $1.44 in the quarter compared with the year-ago period’s loss of 29 cents.PacBio’s Revenues in DetailPacBio registe ...

For the quarter ended March 2025, Pacific Biosciences of California (PACB) reported revenue of $37.15 million, down 4.3% over the same period last year. EPS came in at -$0.15, compared to -$0.26 in the year-ago quarter.The reported revenue represents a surprise of +6.15% over the Zacks Consensus Estimate of $35 million. With the consensus EPS estimate being -$0.19, the EPS surprise was +21.05%.While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they co ...

PacBio Q1 2025 Earnings Presentation May 8, 2025 First Quarter 2025 Earnings Call 1 Statement regarding use of non‐GAAP financial measures This presentation contains "forward-looking statements" within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the U.S. Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact are forward-looking statements, including statements relating to PacBio's cost-saving plans and initiatives as w ...

Revenue Performance - Preliminary Q1 2025 revenue was $36.9 million, a decrease of 5% from $38.8 million in Q1 2024[3]. - Instrument revenue declined to $10.8 million from $19.0 million year-over-year, while consumable revenue increased to a record $20.1 million from $16.0 million[3][4]. - The full-year 2025 revenue guidance remains at $155 million to $170 million[7]. Cost Management - The company plans to reduce annualized non-GAAP operating expenses by $45 million to $50 million, adjusting previous guidance from $270 million to $280 million[5][9]. - The company expects 2025 non-GAAP gross margin to be between 35% and 40%[15]. Sales and Demand - Annualized Revio pull-through per system was approximately $236,000, consistent with expectations in the low to mid $200,000s range[4][15]. - Vega system orders accelerated in Q1 2025 compared to Q4 2024, indicating strong demand from both new and existing customers[4]. Financial Position - Cash, cash equivalents, and investments totaled $343.1 million, down from $561.9 million in Q1 2024[3]. Organizational Changes - The company is restructuring its commercial organization to improve sales force efficiency while maintaining customer service across all segments[6]. Future Outlook - PacBio aims to achieve positive cash flow by the end of 2027 despite ongoing market uncertainties[6].

MENLO PARK, Calif., May 08, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB) today announced financial results for the quarter ended March 31, 2025. First quarter results: Q1 2025Q1 2024Revenue$37.2 million$38.8 millionInstrument revenue$11.0 million$19.0 millionConsumable revenue$20.1 million$16.0 millionService and other revenue$6.0 million$3.8 million<td style="borde ...

Core Insights - PacBio and Chulalongkorn University have announced a strategic collaboration to implement PacBio's HiFi whole genome sequencing (WGS) in a newborn screening research program, marking the first initiative of its kind in the Asia Pacific region [1][2] - The collaboration aims to enhance the identification of rare and treatable conditions in newborns through comprehensive genomic data, positioning Thailand as a leader in precision medicine [1][3] Company Overview - PacBio is a leading provider of high-quality sequencing platforms, focusing on advanced sequencing solutions that address complex genetic problems across various research applications, including human germline sequencing and oncology [4] - The company's HiFi long-read sequencing technology is designed to generate highly accurate and complete genomic data, enabling the detection of a wider range of genetic variants [2][4] Industry Context - Traditional newborn screening programs have been limited to targeted panels, but advances in genome sequencing allow for a broader approach that can identify conditions from birth [2] - The collaboration reflects a growing trend in the Asia Pacific region towards integrating whole genome sequencing into national healthcare strategies, particularly in newborn screening [3]

Company Performance - Pacific Biosciences of California (PACB) closed at $1.11, reflecting a -1.77% change from the previous day, underperforming the S&P 500's gain of 0.58% [1] - Over the past month, PACB shares have decreased by 4.24%, compared to a 5.22% loss in the Medical sector and a 0.84% loss in the S&P 500 [1] Upcoming Earnings - The company is expected to report an EPS of -$0.19, which represents a 26.92% increase from the same quarter last year [2] - The Zacks Consensus Estimate for revenue is projected at $35 million, indicating a decline of 9.82% from the previous year [2] Fiscal Year Estimates - For the entire fiscal year, the Zacks Consensus Estimates predict an EPS of -$0.71 and revenue of $158.74 million, reflecting changes of +14.46% and +3.07% respectively from the prior year [3] Analyst Estimates - Recent changes in analyst estimates for Pacific Biosciences are important as they reflect short-term business trends, with positive revisions indicating analyst optimism about the company's profitability [4] - The Zacks Consensus EPS estimate has decreased by 0.95% in the past month, and the company currently holds a Zacks Rank of 3 (Hold) [6] Industry Context - The Medical - Instruments industry, which includes Pacific Biosciences, has a Zacks Industry Rank of 54, placing it in the top 22% of over 250 industries [7] - Research indicates that the top 50% rated industries outperform the bottom half by a factor of 2 to 1 [7]