Independent Non-Executive Director Appointed
GlobeNewswire· 2025-05-04 22:36
Core Viewpoint - Paladin Energy Ltd has appointed Anne Templeman-Jones as an independent non-executive director, effective May 5, 2025, which is expected to enhance the company's governance and strategic direction [1][5]. Company Overview - Paladin Energy Ltd is recognized as a proven developer and uranium producer with a multi-decade growth pipeline of projects [5]. New Appointment Details - Anne Templeman-Jones brings extensive experience in finance, corporate, and private banking, having held senior positions at ANZ Bank and Westpac [2]. - She has a diverse portfolio of Board roles, including positions with Commonwealth Bank of Australia, Worley Limited, The Trifork AG Group, and GUD Holdings Limited [3]. - Templeman-Jones has contributed to public Boards, notably as a director of the Cyber Security Cooperative Research Centre, which manages a $300 million Federal Government fund [4]. Board Contributions - As Chair Elect of the Audit and Risk Committee, Templeman-Jones will focus on audit, risk, technology transformation, and financing, which are critical areas for the Board and shareholders [5].
Preliminary Phase 1b/2 Data for REC-4881 in Familial Adenomatous Polyposis (FAP) Demonstrates Reduced Polyp Burden
GlobeNewswire· 2025-05-04 16:45
Core Insights - Recursion announced preliminary safety and efficacy results from its Phase 1b/2 TUPELO trial of REC-4881, an investigational MEK1/2 inhibitor for Familial Adenomatous Polyposis (FAP) [1][5] Company Overview - Recursion is a clinical-stage TechBio company focused on decoding biology to improve lives, utilizing its Recursion OS platform to analyze biological and chemical datasets [23] - The company has received Fast Track and Orphan Drug designations from the U.S. FDA for REC-4881, which is aimed at treating FAP, a rare inherited disorder [2] Clinical Trial Details - The TUPELO trial is evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of REC-4881 in patients with FAP [6][8] - The Phase 1b portion was a randomized, double-blind, placebo-controlled safety run-in, while the ongoing Phase 2 portion is open-label [7][8] Efficacy Results - As of March 17, 2025, REC-4881 treatment led to a preliminary median 43% reduction in polyp burden at Week 13 among six efficacy-evaluable patients [3][10] - Five out of six patients (83%) experienced reductions in polyp burden ranging from 31% to 82%, while one patient showed a 595% increase from baseline [3][10] - Three of six patients (50%) achieved a ≥1-point reduction in Spigelman stage, indicating improvement in disease severity [11] Safety Profile - Among 19 safety-evaluable patients, 79% experienced at least one treatment-related adverse event (TRAE), with the majority being Grade 1 or 2 [4][16] - The most frequent TRAEs included acneiform rash, diarrhea, and decreased left ventricular ejection fraction (LVEF) [4][17] - Grade 3 TRAEs occurred in 16% of patients, with no Grade ≥4 events reported [4][18] Next Steps - Patient enrollment in the TUPELO trial is ongoing, with additional efficacy and safety analyses anticipated in the second half of 2025 [21]
Boly’s High Performance Concentrated Solar Products Move into Mass Production
GlobeNewswire· 2025-05-04 02:36
Core Insights - Boly Inc. has introduced BolySolar 3D, a new solar energy product that significantly enhances power generation and efficiency [1][2] - The product utilizes patented 3D light reception structures, allowing it to generate up to 50% more power compared to traditional PV panels, with longer working hours [2][3] - Boly Inc. aims to make clean energy affordable and accessible globally, with a focus on energy stability and reduced storage needs [3][4] Company Overview - Boly Inc. was established in 2002 and operates subsidiaries in California, Shenzhen, and Hong Kong, holding over 100 patents in imaging and Clean Tech [4] - The company's mission is to provide stable clean energy solutions to the world [4] Product Features - BolySolar 3D operates for 11 hours, compared to the 9 hours of conventional panels, while also being cost-effective [2] - The product is designed to be hail-resistant, enhancing its durability and reliability [2]
Sovereignty Wins the 151st Running of the Kentucky Derby Presented by Woodford Reserve
GlobeNewswire· 2025-05-04 01:59
Core Insights - Churchill Downs Incorporated (CDI) set new all-time records for wagering during the Kentucky Derby Day program and Derby Week, indicating strong growth in the betting segment [3][4][5] Wagering Records - Total wagering on Kentucky Derby Day reached $349.0 million, surpassing last year's record of $320.5 million [3] - Wagering on the Kentucky Derby race alone hit a record of $234.4 million, up from $210.7 million last year [3] - All-sources handle for Derby Week increased to $473.9 million, exceeding last year's $446.6 million [3] Performance of TwinSpires - TwinSpires, the official betting partner, recorded a new high of $108.0 million in wagering for the Kentucky Derby Day program, compared to $92.1 million last year [4] - TwinSpires' handle for the Kentucky Derby race was $73.0 million, up from $60.9 million in the previous year [4] Company Financial Expectations - CDI anticipates that Adjusted EBITDA for Derby Week will rank among the top two results in the company's history, although it is expected to be $2 to $4 million lower than last year's record [5] - The company expressed optimism about future growth following the successful 151st running of the Kentucky Derby [6] Company Overview - CDI has been a leader in entertainment experiences for over 150 years, primarily through the Kentucky Derby and has expanded into various gaming and wagering sectors [8]
IBA launches QUASAR® GRID3D Advantage Image Distortion Analysis System
GlobeNewswire· 2025-05-03 14:30
Core Insights - IBA has launched the QUASAR GRID Advantage Image Distortion Analysis System, enhancing quality assurance in MR-guided radiation therapy and MR simulation planning [1][2]. Company Overview - IBA (Ion Beam Applications S.A.) is a leader in particle accelerator technology and a major provider of dosimetry and quality assurance solutions, employing approximately 2,100 people globally [6][7]. - The company is recognized for its advanced proton therapy equipment and services, which are considered the most sophisticated form of radiation therapy available today [6]. Product Features - The GRID Advantage system is designed for facilities needing precise MR distortion analysis for stereotactic planning, ensuring geometric fidelity in MR images [2][3]. - It offers automated analysis through user-friendly software and includes versatile multi-use solutions with various frame adapters or frameless options [2]. Industry Context - The use of MR in radiation therapy is increasing due to its superior soft tissue contrast without ionizing radiation, making precise imaging critical for effective tumor targeting and protection of healthy tissue [3]. - The introduction of robust QA tools like GRID Advantage is essential to maintain image fidelity and enhance clinical confidence in treatment accuracy [3][4]. Expert Commentary - Industry experts highlight that the GRID Advantage represents a significant advancement in quality assurance for Gamma Knife radiosurgery, emphasizing the importance of geometric distortion QA in radiation therapy workflows [4].
Mustang Energy Corp. Provides Update on Geophysical Reinterpretation and Targeting
GlobeNewswire· 2025-05-03 00:10
Core Insights - Mustang Energy Corp. is advancing its exploration strategy in the Athabasca Basin through collaboration with Resource Potentials Ltd. for geophysical reprocessing and reinterpretation of data [1][19] - The company is focusing on cost-effective data integration to enhance its uranium projects [1] Geophysical Reinterpretation Methodology - Resource Potentials has reprocessed high-resolution airborne datasets, including magnetic, radiometric, gravity, and electromagnetic data, sourced from open-file surveys [2] - The integration of these datasets with geological maps and other data in GIS software has been conducted to improve the understanding of the Athabasca Basin [2] Targeting Areas of Interest - The reinterpretation has identified multiple areas of interest, including: - **914W Project**: Located 45 km south of the Athabasca Basin edge, featuring an EM conductor anomaly and a magnetic low [7] - **Spur Project**: Situated 30 km south of the Basin, intersected by regional magnetic-low and EM conductor trends [8] - **Ford Lake**: Comprising three claim blocks near the southern edge of the Basin, with a strong untested EM conductor anomaly [10] - **Cigar Lake East**: Located near the eastern edge of the Basin, featuring multiple magnetic-low trends associated with known uranium mineralization [12] Ongoing and Future Work - Continuous interpretation of newly acquired airborne geophysical surveys is underway, including a MobileMT survey over the Yellowstone Project and an Xcite™ TDEM survey over the Dutton Project [6] - The company plans to initiate field-based prospecting programs to further assess priority targets identified through the reinterpretation [7] Company Overview - Mustang Energy is focused on acquiring and developing uranium and critical mineral assets, holding 92,211 hectares in the Athabasca Basin [19] - The company’s projects include Ford Lake (7,743 hectares), Cigar Lake East (3,442 hectares), Spur Project (17,929 hectares), Yellowstone Project (21,820 hectares), and Dutton Project (7,633 hectares) [19]
MarketWise to Present at the UBS SMID-Cap Multisector Virtual Conference on June 24, 2025
GlobeNewswire· 2025-05-02 23:45
Company Overview - MarketWise, Inc. is a leading multi-brand digital subscription services platform that provides premium financial research, software, education, and tools for self-directed investors [4] - The company has over 25 years of operating history and serves millions of free and paid subscribers [5] - MarketWise operates as a 100% digital, direct-to-customer company, offering its research across various platforms including mobile, desktops, and tablets [5] Upcoming Events - The Chief Financial Officer, Erik Mickels, will host virtual meetings at the UBS SMID-Cap Multisector Virtual Conference on June 24, 2025 [1] - The inaugural UBS SMID-Cap Multisector Virtual Conference aims to showcase small and mid-cap companies and connect them with diverse investors across multiple US regions [3]
HPQ Files Annual Financial Disclosure
GlobeNewswire· 2025-05-02 23:42
Core Viewpoint - HPQ Silicon Inc. has filed its audited annual financial statements and related documents for the fiscal year ended December 31, 2024, and is now focusing on addressing inquiries from the Quebec regulatory authority to lift a temporary trading halt [1][2]. Group 1: Company Developments - The Required Filing was completed in French to comply with the regulations of Quebec's L'Autorité des Marchés Financiers (AMF), with an English version to follow [2]. - The company confirms that there are no ongoing legal proceedings against it and that all material information has been disclosed [3]. Group 2: Company Overview - HPQ Silicon Inc. is a Quebec-based Tier 1 Industrial Issuer on the TSX Venture Exchange, focusing on developing green processes for critical materials to achieve net zero emissions [4]. - The company collaborates with technology partners PyroGenesis Canada Inc. and NOVACIUM SAS to advance its initiatives [4]. Group 3: Strategic Pillars - HPQ aims to become a low-cost manufacturer of Fumed Silica using its proprietary FUMED SILICA REACTOR technology [6]. - The company is working on producing silicon-based anode materials for battery applications with NOVACIUM SAS's assistance [6]. - An affiliate of HPQ, NOVACIUM SAS, is developing a low carbon, chemical-based hydrogen production system [6]. - Another initiative involves transforming black aluminum dross into a valuable resource [6]. - HPQ is also focused on becoming a zero CO2 producer of High Purity Silicon using its PUREVAP "Quartz Reduction Reactors" technology [6].
MarketWise Declares Quarterly Dividend of $0.20 Per Share on Common Stock; Announces Special Dividend of $0.10 Per Share
GlobeNewswire· 2025-05-02 23:22
Core Points - MarketWise, Inc. declared a quarterly cash dividend of $0.20 per share for Class A common stock and a comparable distribution for MarketWise, LLC units [1] - A special dividend of $0.10 per share for Class A common stock was also announced, totaling approximately $0.3 million [2] - Both the regular and special dividends will be paid on June 25, 2025, with a Record Date of May 15, 2025 [2] Company Overview - MarketWise is a leading multi-brand digital subscription services platform focused on providing premium financial research, software, education, and tools for self-directed investors [3] - The company has over 25 years of operating history and serves millions of free and paid subscribers [4] - MarketWise operates as a 100% digital, direct-to-customer company, offering its research across various platforms including mobile, desktops, and tablets [4] - The company's vision is to become the leading financial solutions platform for self-directed investors [4]
Abaxx Files Early Warning Report with Respect to Base Carbon
GlobeNewswire· 2025-05-02 22:00
TORONTO, May 02, 2025 (GLOBE NEWSWIRE) -- Abaxx Technologies Inc. (CBOE: ABXX) (OTCQX: ABXXF) (“Abaxx” or the “Company”) announces today that it has filed an early warning report in respect of its holdings in Base Carbon Inc. (“Base”). On May 2, 2025, Abaxx acquired 3,700,000 common shares of Base by way of private agreement (the “Acquisition”) for an aggregate purchase price of C$1,515,150 at C$0.4095 per common share. At the time of filing its audited consolidated financial statements for the fiscal year ...