Investment Rating - The report maintains an "Outperform" rating for Sichuan Kelun-Biotech Biopharmaceutical with a target price of HKD 297.20, reflecting an upward revision of 48.5% from the previous target price of HKD 200.1 [2][22]. Core Insights - The company has entered a phase where R&D collaboration revenue and commercial sales serve as dual growth drivers, with a sales team expanding to 360 members by the end of 2024 [4][15]. - The company reported a revenue of RMB 1.93 billion for 2024, a 25.5% year-over-year increase, with a gross profit of RMB 1.27 billion and a gross margin of 65.9%, up 16.6 percentage points [3][14]. - Regulatory and R&D catalysts are expected to be abundant in 2025, with three NDAs submitted that are likely to be approved within the year, contributing to incremental revenue growth [5][19]. Financial Performance - Revenue forecasts for 2025-2027 have been adjusted to RMB 1.96 billion, RMB 2.98 billion, and RMB 4.47 billion, reflecting year-over-year growth of +1.4%, +52.2%, and +49.9% respectively [21]. - The net profit forecast for 2025-2027 has been revised to -RMB 280 million, RMB 240 million, and RMB 1.02 billion, showing a significant improvement from previous estimates [21]. - As of December 31, 2024, the company had cash and financial assets of RMB 3.08 billion, reflecting a 21.6% year-over-year increase [3][14]. Product Pipeline and Market Potential - The company has three approved products covering five indications, with ongoing clinical trials for SKB264 and other promising molecules in its pipeline [4][16]. - SKB264 has seen steady sales growth since its market launch in November 2024, with peak sales estimated to reach USD 6-7 billion [16]. - A167, the first PD-L1 inhibitor approved for nasopharyngeal carcinoma, holds significant commercial potential due to the high prevalence of the disease in China [17]. Valuation Methodology - The valuation is based on a DCF model with a weighted average cost of capital of 9.4% and a terminal growth rate of 3.5%, leading to a target price of HKD 297.20 per share [22].
科伦博泰生物-B（06990）：研发合作收入+商业化销售双轮驱动