New REVEAL-1 study results show early signs of weight maintenance after GLP-1 discontinuation REMAIN-1 pivotal study now more than 50% enrolled; midpoint data analysis anticipated in Q3 2025 BURLINGTON, Mass., April 01, 2025 (GLOBE NEWSWIRE) -- Fractyl Health, Inc. (Nasdaq: GUTS) ("the Company"), a metabolic therapeutics company focused on pattern breaking approaches that treat root causes of obesity and type 2 diabetes (T2D), today announced positive early data from the open-label REVEAL-1 cohort of its on ...

The dietitian formulated, doctor-approved GLP-1 Support from Whole Health Rx™ by The Vitamin Shoppe® range of supplements delivers comprehensive nutritional solutions for individuals on GLP-1 weight- loss medications SECAUCUS, N.J., March 31, 2025 /PRNewswire/ -- The Vitamin Shoppe®, a leading omni-channel specialty retailer of nutritional products, today announced the launch of GLP-1 Support from Whole Health Rx™ by The Vitamin Shoppe®, an innovative line of dietary supplements designed to address the uniq ...

Mounjaro and Zepbound are Eli Lilly's largest sources of growth, but there is much more to the company.Over the last couple of years, the pharmaceutical sector has captivated investors thanks in large part to novel medications used to treat chronic weight management and diabetes.While you may be more familiar with brand names such as Ozempic or Wegovy, these drugs are known as glucagon-like peptide-1 (GLP-1) agonists in the medical world. Eli Lilly (LLY -2.98%) has emerged as one of the hottest stocks in th ...

If you like what you have just read and want to receive at least 4 exclusive stock tips every week focused on Pharma, Biotech and Healthcare, then join me at my marketplace channel, Haggerston BioHealth . Invest alongside the model portfolio or simply access the investment bank-grade financial models and research. I hope to see you there.When I last covered Structure Therapeutics (NASDAQ: GPCR ) in a note for Seeking Alpha back in August last year, I gave the South San Francisco-based biotech's stock a "Buy ...

When it comes to clinical weight-loss treatments, GLP-1 therapies have taken the medical sector by storm. What started as off-label use by celebrities and social media influencers for cutting weight became a viral sensation as type 2 diabetes medicine Ozempic kicked off the GLP-1 trend. Novo Nordisk A/S NYSE: NVO formulated a semaglutide treatment specially designed for obesity when they launched Wegovy in June of 2021. Eli Lilly & Co. NYSE: LLY launched its own GLP-1/GIP dual agonist treatment for obesity, ...

Novo Nordisk A/S NYSE: NVO has declared that its GLP-1 drugs for chronic obesity, under the brands Ozempic and Wegovy, are no longer in short supply. This caused the United States Food and Drug Administration (FDA) to take semaglutide, the active ingredient in both, off the drug shortage list on February 21, 2025. This announcement sent shockwaves through shares of Hims & Hers Health Inc. NYSE: HIMS, triggering an immediate 25% sell-off on the news from $59.60 to $49.28 and continued to sink another 33% to ...

Core Insights - Teladoc Health has entered into a pharmacy integration agreement with Eli Lilly's LillyDirect pharmacy partner, Gifthealth, to enhance access to FDA-approved Zepbound® (tirzepatide) for members in its Comprehensive Weight Care Program [1][2] - The integration aims to provide seamless delivery of Zepbound® directly to patients' homes, ensuring visibility throughout the fulfillment process [2][3] - The partnership emphasizes the commitment to reducing barriers to high-quality care and providing affordable access to effective weight management treatments [3][4] Company Overview - Teladoc Health is a leader in virtual care, focusing on transforming healthcare experiences and improving health outcomes through personalized interactions and data-driven insights [6] - The company offers a Comprehensive Weight Care Program that includes multi-disciplinary support from licensed clinicians, registered dietitians, and health coaches, along with tools like connected digital scales and personalized lifestyle coaching [3][6] - The integration with LillyDirect and Gifthealth is part of Teladoc's strategy to enhance patient safety and sustainable health outcomes while avoiding risks associated with compounded medications [3][4]

I am a full-time analyst interested in a wide range of stocks. With my unique insights and knowledge, I hope to provide other investors with a contrasting view of my portfolio, given my particular background.If you have any questions, feel free to reach out to me via a direct message on Seeking Alpha or leave a comment on one of my articles.Analyst’s Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the ...

Global Partners (GLP) Q4 2024 Earnings Call February 28, 2025 05:08 PM ET Company Participants Sean T. Geary - Chief Legal OfficerEric Slifka - President and CEOGregory Hanson - Chief Financial OfficerSelman Akyol - Managing Director - Energy & Power sectorMark Romaine - COO Operator Good day, everyone, and welcome to the Global Partners Fourth Quarter and Full Year twenty twenty four Financial Results Conference Call. Today's call is being recorded. With us from Global Partners are President and Chief Exec ...

Financial Commitments and Sales - As of December 31, 2024, the company had a total commitment of $1.55 billion in credit facilities, including a working capital revolving credit facility of $950 million and a revolving credit facility of $600 million[29]. - In 2024, the company's sales distribution was approximately 63% from Wholesale, 31% from GDSO, and 6% from Commercial segments[30]. - Gasoline sales accounted for 67% of total consolidated sales in 2024, while distillates contributed 30%[37]. - The company issued $450 million in senior notes due 2032 at an interest rate of 8.250% to repay a portion of borrowings and for general corporate purposes[29]. Operations and Infrastructure - The company operated a portfolio of 1,584 gasoline stations as of December 31, 2024, including 300 company-operated locations[57]. - The company owned, leased, or maintained dedicated storage facilities at 54 bulk terminals with a collective storage capacity of approximately 22 million barrels[46]. - The company has a controlled trading program with an aggregate outright commodity exposure of up to 250,000 barrels at any one time[63]. - The company experienced higher gasoline demand during the late spring and summer months, while heating oil demand peaked in the winter months[60]. Employee and Workforce - The company employs approximately 4,840 employees, including about 3,330 full-time employees, as of December 31, 2024[71]. - The company has launched an Employee Relief Fund to support employees during times of need, emphasizing its commitment to employee well-being[76]. - The company has competitive compensation and benefits programs designed to attract and retain talent, including health insurance and retirement savings plans[72]. Environmental Compliance and Regulations - The company is subject to extensive environmental laws that may impose new obligations and affect its business activities[82]. - The company monitors its operations for compliance with environmental laws and regulations, which may incur significant future costs[88]. - The company has obligations to retire sufficient Renewable Identification Numbers (RINs) to cover its Renewable Volume Obligation (RVO), which may lead to mark-to-market liabilities if RINs are insufficient[69]. - The company believes it is in substantial compliance with hazardous substance releases and waste handling requirements, but future regulations could increase operating and compliance costs[93]. - The company holds discharge permits for its facilities and operates in material compliance, although there have been periodic permit discharge exceedances[100]. - The company is subject to the Clean Water Act, which imposes restrictions on pollutant discharges and may require additional permits due to ongoing regulatory changes[99]. - The company has a comprehensive program for underground storage tanks to ensure compliance with environmental regulations, which may require significant future capital expenditures[98]. - The company is aware of no changes to air quality regulations that will materially affect its financial condition or operations[101]. - The company currently reports under the Mandatory Greenhouse Gas Reporting Rule due to the volume of petroleum products imported, which may limit import capabilities or increase costs[112]. - The company faces uncertainty regarding future GHG regulations, which could impact operations and market demand for its products[114]. - The company is subject to potential litigation related to climate change, which could adversely affect its operations in the future[115]. - The SEC released a final rule in March 2024 for climate risk reporting, but its future is uncertain due to ongoing legal challenges[118]. - California has enacted new laws for additional climate-related disclosures, which may increase compliance costs and affect access to capital[118]. Renewable Energy and Fuel Standards - The Renewable Fuel Standard mandates a certain amount of renewable fuels, including ethanol, to be used in transportation fuels each year[121]. - The EPA's final "Set" rule for 2023-2025 under the RFS program may lead to increased costs for renewable fuels and reduced fuel consumption[123]. - The EPA has finalized more stringent methane rules in December 2023, which could impose significant operational costs and compliance requirements[109]. - Starting in 2024, the Inflation Reduction Act imposes a fee on methane emissions, beginning at $900 per metric ton and increasing to $1,500 by 2026[111]. - The EPA's final methane rules and the IRA's fee could accelerate a transition away from fossil fuels, potentially lowering fuel consumption and adversely affecting business[111]. - The EPA's final "Set" rule for biofuel targets increases the renewable volume obligation, likely resulting in higher fuel costs and reduced revenues[122]. Risk Management and Insurance - The company maintains insurance for environmental matters, but coverage may not be sufficient for all risks[125]. - Increased security measures due to terrorism threats have resulted in higher operational costs[126]. - The company believes it is in substantial compliance with hazardous materials transportation regulations, but future regulatory changes could increase costs[133]. - The company believes it is in substantial compliance with OSHA requirements, ensuring worker health and safety[134].