Pfizer on Monday said it would end development of its experimental daily weight loss pill after a patient experienced a liver injury that was potentially caused by the drug in a trial. The patient did not experience any liver-related symptoms or side effects, a Pfizer spokesperson said in a statement. They added that the patient's liver enzymes "recovered rapidly" after they stopped taking the pill, which is an oral GLP-1 drug called danuglipron. The statement suggests that the patient's liver enzymes were ...

Core Viewpoint - Pfizer's shares have been declining for three years, but they may present a buying opportunity for long-term investors [1][2] Group 1: Impact of Tariffs - Pfizer is well-positioned to handle potential tariffs due to its significant manufacturing capacity in the U.S. [3][4] - The company operates the largest U.S.-based manufacturing network in the pharmaceutical industry, with 13 operational sites [4] - Unlike many drugmakers, Pfizer can shift manufacturing operations to the U.S. to avoid tariffs, which could lead to cost savings [5][6] Group 2: Financial Performance - Pfizer's revenue for 2024 increased by 7% year over year to $63.6 billion, with a 12% growth rate excluding contributions from its coronavirus products [8] - The company has reduced its reliance on its coronavirus products, Comirnaty and Paxlovid, which generated a combined $11.1 billion [7][8] - Pfizer's acquisition of Seagen for $43 billion has strengthened its oncology business and expanded its pipeline, which includes over 100 candidates across various therapeutic areas [9] Group 3: Valuation and Future Outlook - Pfizer's forward price-to-earnings (P/E) ratio is 7.6, significantly lower than the healthcare industry's average of 15.8, indicating that the stock is undervalued [12] - The company is focused on launching new products to establish a strong foundation for future growth [10][11]

Pfizer (PFE) ended the recent trading session at $21.91, demonstrating a +1.48% swing from the preceding day's closing price. The stock lagged the S&P 500's daily gain of 1.81%. On the other hand, the Dow registered a gain of 1.56%, and the technology-centric Nasdaq increased by 2.06%.The drugmaker's stock has dropped by 15.66% in the past month, falling short of the Medical sector's loss of 12.01% and the S&P 500's loss of 6.14%.The investment community will be paying close attention to the earnings perfor ...

Pfizer’s (PFE) stock hit a new 52-week low of $20.92 on Wednesday but recovered thereafter and closed at $22.49Though the stock has seen ups and downs in the past year, the latest price decline is largely due to the global uncertainty caused by the tariff war. With the Trump administration imposing sweeping tariffs, fears of a global recession resulted in a stock market rout worldwide. Though pharmaceuticals have been exempted from tariffs this time around, they could well be Trump’s target in the next roun ...

Group 1 - Pfizer Inc. is facing significant challenges, particularly low investor sentiment and a declining stock price [1] - The company is categorized as a healthcare giant and is publicly traded on the NYSE under the ticker symbol PFE [1] Group 2 - The article does not provide specific financial metrics or performance data related to Pfizer Inc. [1]

Analyst's Disclosure: I/we have a beneficial long position in the shares of PFE either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article. Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any in ...

While the proven Zacks Rank places an emphasis on earnings estimates and estimate revisions to find strong stocks, we also know that investors tend to develop their own individual strategies. With this in mind, we are always looking at value, growth, and momentum trends to discover great companies.Considering these trends, value investing is clearly one of the most preferred ways to find strong stocks in any type of market. Value investors rely on traditional forms of analysis on key valuation metrics to fi ...

Core Viewpoint - The narrative surrounding Pfizer is currently negative, but this presents an interesting investment opportunity as the stock price has significantly declined from its peak during the COVID-19 pandemic [1][2]. Financial Performance - Pfizer's stock has decreased over 63% from its peak in 2022, following a sell-off in the market [1]. - The dividend yield has increased to 7.5%, providing a substantial annual return for investors as long as the dividend is maintained [4]. - Pfizer's price-to-earnings ratio is currently less than 8 times the 2025 earnings estimates, indicating a low valuation [5]. Dividend Sustainability - The high dividend yield is more a reflection of negative market sentiment rather than a sign of unsustainable business fundamentals [6][7]. - Pfizer's management recently raised the quarterly dividend, and the annual payout of $1.72 per share represents only 61% of the lower end of the 2025 earnings guidance [7]. Growth Potential - Pfizer's pipeline includes promising drugs, such as danuglipron for diabetes, which could tap into a market projected to exceed $150 billion by 2030 [11]. - The company has made strategic acquisitions, such as Seagen for $43 billion, to bolster its oncology business [11]. - Despite potential declines in sales due to patent expirations for key products, Pfizer's pipeline and acquisitions position it for future growth [10][11]. Market Outlook - Analysts have varying long-term earnings growth expectations for Pfizer, ranging from 2.5% to over 13.8% [12]. - Even with minimal growth, the stock could still deliver 10% annualized total returns due to the dividend, with potential for higher returns if growth exceeds expectations [13].

Core Insights - Pfizer and Moderna were the two leading companies in developing effective coronavirus vaccines, achieving significant financial success during the pandemic [1] - Both companies have experienced a substantial decline in revenue and share prices as the pandemic has receded, raising questions about their future performance [2] Pfizer - Pfizer has made strategic moves, including the approval of new medicines and vaccines, and a significant acquisition of Seagen for $43 billion, enhancing its oncology pipeline [3] - In 2024, Pfizer reported a revenue of $63.6 billion, a 7% increase from the previous year, with adjusted earnings per share of $3.11, reflecting a 69% year-over-year growth [4] - The company continues to generate sales from its COVID-19 products, Comirnaty and Paxlovid, which contributed approximately $11.1 billion in sales in 2024 [4] - Pfizer is expected to navigate upcoming patent cliffs successfully, supported by its ongoing product approvals and a strong dividend yield of 6.8%, with a 53.6% increase in payouts over the past decade [5][6] Moderna - Moderna's total revenue in 2024 fell nearly 53% year-over-year to $3.2 billion, with a net loss per share of $9.28, although this was an improvement from the previous year's loss [7] - The company has received approval for an RSV vaccine and is awaiting further label expansions, indicating potential growth opportunities [8] - Moderna's combination COVID/influenza vaccine showed promising results in a phase 3 study, and the company is pursuing multiple late-stage studies for innovative products, including a personalized cancer vaccine [9][10] - The mRNA platform has demonstrated success, and if Moderna continues to achieve positive clinical results and regulatory approvals, its financial performance may improve [10] Comparative Analysis - Pfizer is characterized as a well-established pharmaceutical giant with consistent revenue from a diverse product portfolio, while Moderna is a smaller biotech company with fewer profitable products [11] - Pfizer outperforms Moderna in key financial metrics such as total sales, profits, and free cash flow, and it also offers dividends, making it attractive for income-seeking investors [12] - While Pfizer is viewed as the better investment option for most investors, Moderna may present higher upside potential for those willing to accept greater risk and volatility [13]

Company Performance - Pfizer's stock closed at $24.70, reflecting a +0.65% change, which lagged behind the S&P 500's gain of 0.67% [1] - Over the past month, Pfizer's shares have decreased by 4.7%, compared to the Medical sector's loss of 5.32% and the S&P 500's loss of 5.28% [1] Upcoming Earnings - Pfizer's earnings report is scheduled for April 29, 2025, with projected EPS of $0.68, indicating a 17.07% decline from the same quarter last year [2] - The consensus estimate for quarterly revenue is $13.99 billion, down 5.97% year-over-year [2] Full-Year Estimates - Full-year earnings estimates for Pfizer are $2.97 per share and revenue of $63.2 billion, representing year-over-year changes of -4.5% and -0.67%, respectively [3] - Recent revisions to analyst forecasts are crucial as they reflect short-term business trends, with positive revisions indicating a favorable business outlook [3] Valuation Metrics - Pfizer has a Zacks Rank of 3 (Hold) and a Forward P/E ratio of 8.26, which is below the industry's average Forward P/E of 13.71 [5] - The PEG ratio for Pfizer is currently 0.6, compared to the Large Cap Pharmaceuticals industry's average PEG ratio of 1.31 [6] Industry Context - The Large Cap Pharmaceuticals industry is part of the Medical sector and holds a Zacks Industry Rank of 67, placing it in the top 27% of over 250 industries [6] - The Zacks Industry Rank indicates that the top 50% rated industries outperform the bottom half by a factor of 2 to 1 [7]