Core Insights - Yinosh experienced a stock price increase of 10.46% on November 11, with a trading volume of 163 million yuan [1] - The company reported a significant decline in revenue and net profit for the first nine months of 2025, with revenue of 571 million yuan, down 35.33% year-on-year, and a net loss of 14.79 million yuan, a decrease of 111.14% [2] Financing and Trading Activity - On November 11, Yinosh had a financing buy-in amount of 10.01 million yuan and a net financing outflow of 5.66 million yuan, with a total financing balance of 63.92 million yuan, representing 1.41% of its market capitalization [1] - The financing balance is below the 20th percentile of the past year, indicating a low level of financing activity [1] - There were no short sales or repayments on November 11, with the short selling balance at zero, which is at the 90th percentile of the past year, indicating a high level of short selling activity [1] Shareholder and Institutional Holdings - As of September 30, the number of shareholders for Yinosh decreased by 9.97% to 4,849, while the average number of circulating shares per person increased by 257.28% to 18,703 shares [2] - The company has distributed a total of 45.11 million yuan in dividends since its A-share listing [3] - New institutional shareholders include Huatai-PineBridge Healthcare Mixed Fund and Huaxia Stable Growth Mixed Fund, while several funds exited the top ten circulating shareholders list [3]

登录新浪财经APP 搜索【信披】查看更多考评等级 股东询价转让结果报告书暨持股5% 以上股东权益变动触及5% 整数倍的提示性公告 上海张江生物医药基地开发有限公司（以下简称"张江生药基地"或"转让方"）保证向上海益诺思生物技 术股份有限公司（以下简称"益诺思"）提供的信息内容不存在任何虚假记载、误导性陈述或者重大遗 漏，并对其真实性、准确性和完整性依法承担法律责任。 本公司及董事会全体成员保证公告内容与信息披露义务人提供的信息一致。 重要内容提示: ●本次询价转让的价格为35.49元/股，转让的股票数量为4,229,388股。 ●公司控股股东、实际控制人、董事、监事及高级管理人员不参与本次询价转让。 ●本次转让不会导致公司控股股东、实际控制人发生变化。 证券代码：688710 证券简称：益诺思 公告编号：2025-040 上海益诺思生物技术股份有限公司 本次转让导致权益变动的，转让方上海张江生物医药基地开发有限公司持股比例由10.82%减少至 7.82%。 一、转让方情况 (一)转让方基本情况 截至2025年10月31日，转让方所持公司股份的数量、比例情况如下： ■ 本次询价转让的转让方为持股5%以上的股东， ...

Core Viewpoint - The report details a shareholding reduction by Shanghai Zhangjiang Biopharmaceutical Base Development Co., Ltd. in Shanghai Yinos Biotech Co., Ltd., decreasing its stake from 10.82% to 7.82% through a block trade of 4,229,388 shares at a price of 35.49 yuan per share, which does not affect the company's control or governance structure [6][15][20]. Group 1: Shareholding Changes - The information disclosure obligor held 15,250,141 shares before the transaction, representing 10.82% of the total shares, and after the transaction, it holds 11,020,753 shares, which is 7.82% of the total [5][6]. - The share reduction was executed through an inquiry transfer method, and the shares transferred cannot be sold by the buyer for six months [3][6]. - The transaction does not lead to a change in the company's controlling shareholder or actual controller [8][15]. Group 2: Transaction Details - The inquiry transfer price was set at 35.49 yuan per share, with the total number of shares transferred being 4,229,388 [15][20]. - The transfer was conducted without participation from the company's controlling shareholders, directors, supervisors, or senior management [15]. - The inquiry process involved 224 institutional investors, with 17 submitting valid bids, resulting in 15 investors receiving allocations [18][20]. Group 3: Compliance and Reporting - The information disclosure obligor confirmed that the report contains no false records, misleading statements, or significant omissions, and it assumes legal responsibility for the report's content [2][11]. - The report complies with relevant laws and regulations, ensuring a fair and transparent transfer process [20].

上海益诺思生物技术股份有限公司 简式权益变动报告书 上市公司名称：上海益诺思生物技术股份有限公司 股票上市地点：上海证券交易所 股票简称：益诺思 股票代码：688710 信息披露义务人：上海张江生物医药基地开发有限公司 住所/通讯地址：中国(上海)自由贸易试验区张江路 625 号 807 室/上海市浦东 新区哈雷路 899 号 A 栋 股份变动性质：股份减少（询价转让） 签署日期：2025 年 11 月 10 日 信息披露义务人声明 第一节 释义 一、信息披露义务人依据《中华人民共和国证券法》（以下简称"《证券法》"）、 《上市公司收购管理办法》（以下简称"《收购办法》"）、《公开发行证券的公 司信息披露内容与格式准则第 15 号——权益变动报告书》（以下简称"《准则 15 号》"）及相关的法律、法规和规范性文件编制本报告书。 二、信息披露义务人签署本报告书已获得必要的授权和批准，其履行亦不违 反信息披露义务人公司章程或内部规则中的任何条款，或与之相冲突。 三、依据《证券法》《收购办法》《准则 15 号》的规定，本报告书已全面 披露了信息披露义务人在上海益诺思生物技术股份有限公司（以下简称"益诺思"、 "上市 ...

证券代码：688710 证券简称：益诺思 公告编号：2025-040 上海益诺思生物技术股份有限公司 股东询价转让结果报告书暨持股 5%以上股东权益 变动触及 5%整数倍的提示性公告 上海张江生物医药基地开发有限公司（以下简称"张江生药基地"或"转让 方"）保证向上海益诺思生物技术股份有限公司（以下简称"益诺思"）提供的信息 内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其真实性、准确性和完 整性依法承担法律责任。 本公司及董事会全体成员保证公告内容与信息披露义务人提供的信息一致。 重要内容提示: 本次转让导致权益变动的，转让方上海张江生物医药基地开发有限公司持股比 例由10.82%减少至7.82%。 一、 转让方情况 | 序号 | 股东名称 | 持股数量（股） | 持股比例 | | --- | --- | --- | --- | | 1 | 张江生药基地 | 15,250,141 | 10.82% | 本次询价转让的转让方为持股 5%以上的股东，非公司的控股股东、实际控制 人、董事、监事及高级管理人员。 (二)转让方一致行动关系及具体情况说明 本次询价转让的出让方无一致行动人。 (三)本次转让具体情况 ...

截至 2025 年 10 月 31 日，转让方所持公司股份的数量、比例情况如下： | 序号 | 股东名称 | 持股数量（股） | 持股比例 | | --- | --- | --- | --- | | 1 | 张江生药基地 | 15,250,141 | 10.82% | 国泰海通证券股份有限公司 关于上海益诺思生物技术股份有限公司 股东向特定机构投资者询价转让股份的核查报告 上海证券交易所： 国泰海通证券股份有限公司（以下简称"国泰海通"或"组织券商"）受委 托担任上海张江生物医药基地开发有限公司（以下简称"张江生药基地"或"转 让方"）以向特定机构投资者询价转让（以下简称"本次询价转让"）方式减持 所持有的上海益诺思生物技术股份有限公司（以下简称"公司"或"益诺思"） 首次公开发行前已发行股份的组织券商。 经核查，国泰海通就本次询价转让的股东、受让方是否符合《上海证券交易 所科创板上市公司自律监管指引第 4 号——询价转让和配售（2025 年 3 月修订）》 （以下简称"《询价转让和配售指引》"）要求，本次询价转让的询价、转让过 程与结果是否公平、公正，是否符合《询价转让和配售指引》的规定作出如下报 告说明。 ...

Core Viewpoint - Yinosh's stock price has shown a significant increase this year, with a notable rise in recent trading days, indicating positive market sentiment towards the company [1]. Group 1: Stock Performance - As of November 10, Yinosh's stock price increased by 2.04%, reaching 45.42 CNY per share, with a trading volume of 33.84 million CNY and a turnover rate of 0.83% [1]. - Year-to-date, Yinosh's stock price has risen by 29.07%, with a 1.66% increase over the last five trading days, 4.73% over the last 20 days, and 7.17% over the last 60 days [1]. Group 2: Financial Performance - For the period from January to September 2025, Yinosh reported a revenue of 571 million CNY, reflecting a year-on-year decrease of 35.33%, and a net profit attributable to shareholders of -14.79 million CNY, a decline of 111.14% compared to the previous year [2]. Group 3: Shareholder Information - As of September 30, 2025, Yinosh had 4,849 shareholders, a decrease of 9.97% from the previous period, while the average number of circulating shares per person increased by 257.28% to 18,703 shares [2]. - The company has distributed a total of 45.11 million CNY in dividends since its A-share listing [3]. - New institutional shareholders include Huatai-PineBridge Healthcare Mixed Fund and Huaxia Stable Growth Mixed Fund, while several funds have exited the top ten circulating shareholders list [3]. Group 4: Company Overview - Yinosh, established on May 12, 2010, is located in the China (Shanghai) Pilot Free Trade Zone and specializes in providing non-clinical research services as part of its comprehensive R&D services (CRO) [1]. - The company's revenue composition is primarily from non-clinical services (96.31%), followed by clinical services (3.42%) and other services (0.27%) [1].

Core Viewpoint - Yinosh experienced a 4.93% increase in stock price on November 5, with a trading volume of 83.7251 million yuan, indicating a positive market response despite a net financing outflow [1] Financing Summary - On November 5, Yinosh had a financing buy-in of 3.1131 million yuan and a financing repayment of 9.9966 million yuan, resulting in a net financing outflow of 6.8835 million yuan [1] - As of November 5, the total financing and securities lending balance for Yinosh was 72.5176 million yuan, which represents 1.76% of its market capitalization, indicating a low financing balance compared to the past year [1] Securities Lending Summary - On November 5, Yinosh had no shares repaid or sold in securities lending, with a total lending balance of 0 shares, which is at a high level compared to the past year [1] Company Overview - Shanghai Yinosh Biotechnology Co., Ltd. was established on May 12, 2010, and is located in the China (Shanghai) Pilot Free Trade Zone [1] - The company specializes in providing comprehensive research and development services (CRO) primarily focused on non-clinical research services, with 96.31% of its revenue coming from non-clinical services [1] Financial Performance - For the period from January to September 2025, Yinosh reported a revenue of 571 million yuan, a year-on-year decrease of 35.33%, and a net profit attributable to shareholders of -14.7881 million yuan, reflecting a year-on-year decrease of 111.14% [2] - Since its A-share listing, Yinosh has distributed a total of 45.1135 million yuan in dividends [2] Shareholder Information - As of September 30, 2025, Yinosh had 4,849 shareholders, a decrease of 9.97% from the previous period, with an average of 18,703 circulating shares per shareholder, an increase of 257.28% [2] - New institutional shareholders include Huatai-PineBridge Healthcare Mixed Fund and Huaxia Stable Growth Mixed Fund, while several funds exited the top ten circulating shareholders list [2]

Investment Rating - The report maintains a "Buy" rating for the company with a target price of 46.92 CNY based on a 46x PE for 2026 [3][5]. Core Insights - The company has seen a significant increase in new orders, with a year-on-year growth of 29.4% in new signed orders for the first three quarters of 2025, indicating a clear turning point in performance [9]. - The company’s revenue for the first three quarters of 2025 was 570 million CNY, reflecting a year-on-year decline of 35.3%, primarily due to intense domestic market competition [9]. - The company is expected to reach an upward performance inflection point in 2026, driven by new capacity ramp-up and strong demand for new molecular drugs [9]. Financial Performance Summary - Revenue projections for 2025-2027 have been adjusted, with expected earnings per share of 0.14 CNY in 2025, 1.02 CNY in 2026, and 1.59 CNY in 2027 [3]. - The company’s gross margin is projected to improve from 27.9% in 2025 to 39.5% in 2027, while net profit margin is expected to rise from 2.4% in 2025 to 17.2% in 2027 [4][12]. - The company’s net profit attributable to the parent company is forecasted to be 20 million CNY in 2025, with a significant recovery to 224 million CNY by 2027 [4][12].

Group 1 - Triangle Defense signed a gas turbine project development and framework order agreement with Siemens Energy [1] - The development agreement allows Triangle Defense to qualify for supplying specific items to Siemens Energy, detailing technical prerequisites and standards [1] - Triangle Defense specializes in the research, production, and sales of forged products in aviation, aerospace, and shipping industries [1] Group 2 - Aerospace Hongtu was suspended from military procurement for three years due to alleged violations during a procurement activity [2] - The suspension will last from July 6, 2024, to July 6, 2027, affecting the company's participation in military material procurement [2] - Aerospace Hongtu focuses on satellite operations and data collection [3] Group 3 - Kaili Medical's executives purchased a total of 460,000 shares, investing approximately 13.15 million yuan [4] - The average purchase prices were 28.70 yuan and 28.53 yuan per share [4] - Kaili Medical is engaged in the research, production, and sales of medical diagnostic and treatment equipment [5] Group 4 - Muyuan Foods reported a 22.28% year-on-year decline in sales revenue from live pigs in October, totaling 10.33 billion yuan [6] - The average selling price of live pigs decreased by 32.73% year-on-year to 11.55 yuan per kilogram [6] - Muyuan Foods is involved in pig farming and slaughtering [7] Group 5 - Niuwei Co. plans to acquire 40% of its subsidiary Dongwu Machinery for 139 million yuan, aiming for full ownership [8] - Niuwei Co. specializes in the research, manufacturing, and sales of industrial valves [9] Group 6 - Jinlong Automobile reported a 14.71% year-on-year decline in bus sales in October, with 4,121 units sold [10] - Jinlong Automobile focuses on the production and sales of bus products [10] Group 7 - ST Tianshan reported a 242.54% year-on-year increase in sales revenue from live livestock in October, totaling 13.35 million yuan [11] - The company sold 1,367 head of livestock, marking a significant increase compared to previous periods [11] - ST Tianshan is involved in the breeding and sales of cattle and dairy products [12] Group 8 - Ningbo Port expects a 12.4% year-on-year increase in container throughput in October, reaching 4.56 million TEUs [13] - The total cargo throughput is projected to be 99.6 million tons, a 5.3% increase year-on-year [13] - Ningbo Port engages in port handling and logistics services [13] Group 9 - Amcare Pharma received approval for supplementary drug applications and clinical trials for its products [14] - The company is focused on new drug development and utilizes a MAH model for production [14] Group 10 - Lude Environment plans to change its stock name to "Lude Technology" while keeping its full name and stock code unchanged [15] - The company specializes in waste treatment and resource utilization technologies [15] Group 11 - Hualan Co. plans to increase its stake in the company by investing between 30 million and 60 million yuan [16] - The maximum purchase price is set at 58.08 yuan per share [16] - Hualan Co. focuses on the development and sales of packaging materials for injectable drugs [16] Group 12 - Caina Co. is using 140 million yuan of idle funds to purchase structured deposits from a bank, with expected annual yields between 0.70% and 1.85% [17] - Caina Co. specializes in the research, production, and sales of injection and laboratory consumables [17] Group 13 - Zhenghong Technology reported a 52.80% year-on-year decrease in sales revenue from live pigs in October, totaling 4.32 million yuan [18] - The company sold 400 head of pigs, marking a significant decline compared to previous periods [18] - Zhenghong Technology is involved in feed production and pig farming [18] Group 14 - Caida Securities received approval from the CSRC to issue bonds totaling up to 6 billion yuan [19] - The company is engaged in securities brokerage, investment banking, and asset management [19] Group 15 - Jiayuan Technology signed a copper foil supply framework agreement with CATL, establishing a long-term partnership [20] - The agreement includes collaboration in the supply and production of materials for new battery technologies [20] Group 16 - Haikong Group announced the resignation of its general manager due to personal career planning [21] - The company is involved in automotive passenger transport and related services [21] Group 17 - Beizhi Technology's application to acquire 100% of Suzhou Suike Intelligent Technology has been accepted by the Shanghai Stock Exchange [22] - The company specializes in intelligent logistics systems and equipment [22] Group 18 - Yikang Pharma's subsidiary received approval for clinical trials of a new injection for chronic hepatitis B [23] - The company focuses on the production and sales of raw and formulated pharmaceutical products [23] Group 19 - Hengyuan Coal Power plans to acquire 100% of two coal companies for 440 million yuan [24] - The acquisition includes assuming debts totaling 1.137 billion yuan [24] - Hengyuan Coal Power is involved in coal mining and sales [24] Group 20 - Yangpu Medical announced the cancellation of a production arrangement for a medical device [25] - The company specializes in precision medical and testing services [25] Group 21 - Kailong High-Tech plans to establish a 195 million yuan industry fund focusing on unlisted companies [26] - The company is involved in air pollution control and new energy management systems [26] Group 22 - Yingli Co. received approval for its application to acquire a majority stake in a company [27] - The company specializes in precision electronic components and related manufacturing [27] Group 23 - Tianyi Medical's arterial-venous puncture device received EU MDR certification, valid until January 2028 [28] - The company focuses on medical devices for blood purification and care [28] Group 24 - Chuangyuan Co. appointed a new president, effective until the end of the current board term [29] - The company specializes in the design and production of paper products [29] Group 25 - Shanghai Laishi's new indication for a drug received clinical trial approval [30] - The company focuses on the production and sales of blood products [30] Group 26 - Fengmao Co. plans to issue convertible bonds to raise up to 520 million yuan for expansion and working capital [31] - The company specializes in precision rubber components [31] Group 27 - Yinuo Si's shareholder plans to transfer 3% of the company's shares through an inquiry process [32] - The company provides comprehensive R&D services in the biopharmaceutical sector [32] Group 28 - Phoenix Shipping plans to use up to 50 million yuan of idle funds for cash management [33] - The company is involved in dry bulk shipping and logistics services [33] Group 29 - Xingyuan Zhuomei received a notification to supply magnesium alloy components worth 2.021 billion yuan to a new energy vehicle manufacturer [34] - The project is expected to start mass production in the third quarter of 2026 [34] Group 30 - Landai Technology's subsidiary plans to sell electric drive assembly assets for 110 million yuan [35] - The company specializes in power transmission and display technology [35] Group 31 - Yuexiu Capital plans to distribute a cash dividend of 0.90 yuan per share [36] - The company is involved in asset management and private equity [36] Group 32 - Northeast Securities plans to distribute a cash dividend of 1.00 yuan per share, totaling 234 million yuan [37] - The company focuses on wealth management and investment banking [37] Group 33 - Jinguang Electric won a bid for a project from the State Grid worth 21.7976 million yuan [38] - The company specializes in the research and manufacturing of power distribution equipment [39] Group 34 - Huarong Co. plans to repurchase shares worth between 40 million and 125 million yuan [40] - The company focuses on the production and sales of explosion-proof electrical equipment [40] Group 35 - Baiyang Pharma signed a distribution agreement for a blood product, gaining exclusive rights in specific markets [41] - The company specializes in the development and commercialization of medical innovations [41] Group 36 - Li Qun Co.'s director plans to reduce his stake by up to 71,000 shares due to personal financial needs [42] - The company is involved in retail and logistics services [42] Group 37 - Su Li Co.'s shareholder plans to reduce his stake by up to 0.48% of the company's shares [43] - The company specializes in the production and sales of fine chemical products [43] Group 38 - Shenzhen Ruijie obtained a commitment letter for a stock repurchase loan of up to 15.3 million yuan [44] - The company provides project management and evaluation services [44] Group 39 - Fudan Zhangjiang's shareholder plans to reduce his stake by up to 1% of the company's shares [45] - The company focuses on biopharmaceutical research and development [45] Group 40 - Ningbo Zhongbai's shareholder plans to reduce his stake by up to 1% of the company's shares [46] - The company is involved in retail and wholesale operations [46] Group 41 - Jingyi Co. announced a change in control due to a judicial auction of shares [47] - The company specializes in copper processing and digital carbon services [47] Group 42 - Luoping Zinc Electric's subsidiary obtained a new safety production license for mining operations [48] - The company focuses on hydropower and mining activities [48]