Group 1 - Longjian Co., Ltd. won a bid for a highway maintenance project in Heilongjiang with a contract value of 483 million yuan, accounting for 2.64% of the company's expected revenue for 2024 [1] - Transsion Holdings plans to issue H-shares and list on the main board of the Hong Kong Stock Exchange [1] - Good Home's controlling shareholder intends to reduce its stake by up to 2.7%, equivalent to no more than 39.4468 million shares [1][2] Group 2 - Xinhua Insurance reported a cumulative premium income of 181.973 billion yuan from January to October, representing a year-on-year growth of 17% [2][4] - Zhejiang Jiaokao is part of a consortium that plans to bid for a new urbanization project with an estimated total investment of 11.103 billion yuan [4] Group 3 - Changchun High-tech received approval for clinical trials of a vaccine for adolescents and adults [6] - XinNuoWei's application for the listing of Pertuzumab injection has been accepted, targeting HER2-positive breast cancer [8] - Dash Smart won a bid for an intelligent project at the new Huanggang Port inspection building, valued at 55.056 million yuan, which is 1.74% of its expected revenue for 2024 [8] Group 4 - Electronic City is involved in a lawsuit for debt recovery, with the amount in dispute estimated at 777 million yuan [9] - Haibo Technology signed a strategic cooperation agreement with CATL for a cumulative procurement of no less than 200 GWh of electricity from 2026 to 2028 [10] Group 5 - Renfu Pharmaceutical's HW231019 tablets have entered the second phase of clinical trials for postoperative pain relief [11] - Tonghua Dongbao received a drug registration certificate for Aspart Insulin injection from the Dominican Republic [11] Group 6 - Shaanxi Construction reported winning major projects worth a total of 1.016 billion yuan in October [12] - Fuzhou Environmental Protection plans to change its stock name to "Fuzhou Technology" [12] Group 7 - Panlong Pharmaceutical's gel patch for knee osteoarthritis has received approval for clinical trials [15] - Zhongyida's application for a specific stock issuance has been terminated by the Shanghai Stock Exchange [16] Group 8 - Zhizhong Home's controlling shareholder reduced its holdings of convertible bonds by 905,000 units, accounting for 13.51% of the total issued [19] - Haibo Co., Ltd. plans to establish a subsidiary with an investment of 1 billion yuan for high-end component projects [21] Group 9 - Caina Co. plans to use 57 million yuan of idle funds to purchase structured deposits [23] - Zhendong Pharmaceutical's new drug for acute ischemic stroke has entered the IIa phase of clinical trials [25] Group 10 - Weiman Sealing's overseas subsidiary plans to lease a factory in Saudi Arabia for 5 years at a total rent of approximately 54.039 million yuan [26] - Yiling Pharmaceutical's application for Memantine Hydrochloride has been approved for market entry [28] Group 11 - Dongfang Zhizao plans to acquire 70% of Saifu Machinery for 27.4887 million yuan [30] - JianKai Technology's actual controller intends to transfer 3% of the company's shares through inquiry [31] Group 12 - Rejing Bio plans to repurchase shares worth between 100 million and 200 million yuan [32] - Bangji Technology has decided to terminate a major asset restructuring project due to failure to reach an agreement [34] Group 13 - Huadong Pharmaceutical's application for the marketing license of a new drug has been accepted [36] - Zhonggu Logistics' shareholder plans to reduce its stake by up to 3% [38] Group 14 - Bohui Innovation's subsidiary received approval for a clinical trial of a vaccine for invasive infections [40] - Shannon Chip's shareholder pledged 0.27% of the company's shares for financing [42] Group 15 - Shanghai Petrochemical appointed a new general manager [44] - Jiaojian Co. plans to reduce the holdings of some directors and executives by up to 0.35% [46] Group 16 - Weiting Electric plans to raise no more than 300 million yuan through a private placement [47] - Zhongjin Irradiation plans to invest approximately 200 million yuan in an electronic accelerator manufacturing project [49] Group 17 - Tongxing Technology signed a framework agreement to invest 3.2 billion yuan in a sodium battery project [50] - Hongri Da plans to establish a subsidiary focused on semiconductor packaging [51] Group 18 - Shanghai Kaibao's new drug for acute ischemic stroke has received approval for clinical trials [53] - Yitong Century announced a change in its control structure, becoming a company without a controlling shareholder [55]

Core Viewpoint - Yiling Pharmaceutical (002603) has stated that its product has not yet conducted clinical trials targeting the virus related to Chikungunya fever [1] Group 1 - Yiling Pharmaceutical responded on November 12 regarding the effectiveness of Lianhua Qingwen in alleviating Chikungunya fever symptoms [1]

Core Viewpoint - Yiling Pharmaceutical (002603.SZ) has indicated that its products have not yet initiated clinical trials targeting Chikungunya fever [1] Group 1 - The company has not commenced any clinical trials for products related to Chikungunya fever [1]

Core Viewpoint - Yiling Pharmaceutical (002603) announced that its wholly-owned subsidiary, Wanyang Hengshui Pharmaceutical Co., Ltd., has received the approval notice for the listing application of Memantine Hydrochloride from the National Medical Products Administration [1] Group 1: Company Developments - Wanyang Hengshui submitted the listing application for Memantine Hydrochloride, which has now been approved [1] - Memantine Hydrochloride is a voltage-dependent, moderate-affinity, non-competitive NMDA receptor antagonist [1] - The drug is indicated for the treatment of moderate to severe Alzheimer's disease by blocking pathological increases in glutamate concentration that lead to neuronal damage [1]

Core Viewpoint - Yiling Pharmaceutical (002603) announced that its wholly-owned subsidiary, Wanyang Hengshui Pharmaceutical Co., Ltd., has received approval from the National Medical Products Administration for the marketing application of Memantine Hydrochloride, a chemical raw material drug [1] Group 1 - The approved drug, Memantine Hydrochloride, is a voltage-dependent, moderate-affinity non-competitive NMDA receptor antagonist [1] - Memantine Hydrochloride is used to block pathological increases in glutamate concentration that lead to neuronal damage, specifically for the treatment of moderate to severe Alzheimer's disease [1]

Core Viewpoint - Yiling Pharmaceutical (002603.SZ) announced that its wholly-owned subsidiary, Wanyang Hengshui Pharmaceutical Co., Ltd., has received the approval notice for the listing application of the chemical raw material drug Memantine Hydrochloride from the National Medical Products Administration [1] Company Summary - The approved drug, Memantine Hydrochloride, is a voltage-dependent, moderate-affinity non-competitive NMDA receptor antagonist [1] - Memantine Hydrochloride is used to block neuronal damage caused by pathological increases in glutamate concentration, specifically for the treatment of moderate to severe Alzheimer's disease [1]

Core Viewpoint - Yiling Pharmaceutical (002603.SZ) announced that its wholly-owned subsidiary, Wanyuan Hengshui Pharmaceutical Co., Ltd., has received approval from the National Medical Products Administration for the listing application of Memantine Hydrochloride, a chemical raw material drug [1] Group 1: Company Information - Yiling Pharmaceutical's subsidiary, Hengshui Wanyuan, submitted the listing application for Memantine Hydrochloride, which has now been approved [1] - Memantine Hydrochloride is a voltage-dependent, moderate-affinity, non-competitive NMDA receptor antagonist that can block pathological increases in glutamate concentration, leading to neuronal damage [1] Group 2: Industry Context - Memantine Hydrochloride is used for the treatment of moderate to severe Alzheimer's disease [1]

证券代码：002603 证券简称：以岭药业 公告编号：2025-043 石家庄以岭药业股份有限公司 关于收到化学原料药上市申请批准通知书的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没 有虚假记载、误导性陈述或重大遗漏。 年中国盐酸美金刚市场容量预计达到 3.4 亿元，同比增长 11%；销售量 1.6 亿片， 同比增长 19%，销售呈现持续增长的趋势。盐酸美金刚被我国和 FDA 批准用于 中重度 AD 患者，国内外指南推荐的一线药物，预计随着中国人口老龄化的进程 加快，盐酸美金刚的市场需求将稳步上升。目前国内已有多家盐酸美金刚原料供 应商，衡水万洋将以本次国内获批为契机，提升市场份额。 三、对公司的影响及主要风险提示 申请事项：境内生产化学原料药上市申请 登记号：Y20240000483 生产企业名称：万洋衡水制药有限公司 主要结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品 符合药品注册的有关要求，批准注册。质量标准、生产工艺及标签照所附执行。 二、药品的基本情况 盐酸美金刚（Memantine Hydrochloride）是一种电压依赖性、中等程度亲和 力的非竞争性 NM ...

Core Viewpoint - Yiling Pharmaceutical (002603.SZ) announced that its wholly-owned subsidiary, Wanyuan Hengshui Pharmaceutical Co., Ltd., has received approval from the National Medical Products Administration for the listing application of Memantine Hydrochloride, a chemical raw material drug [1] Group 1 - The approved drug, Memantine Hydrochloride, is a voltage-dependent, moderate-affinity non-competitive NMDA receptor antagonist [1] - Memantine Hydrochloride can block pathological increases in glutamate concentration that lead to neuronal damage [1] - The drug is indicated for the treatment of moderate to severe Alzheimer's disease [1]

Core Insights - The traditional Chinese medicine sector experienced a rise of 0.84% on November 11, with Weikang Pharmaceutical leading the gains [1] - The Shanghai Composite Index closed at 4002.76, down 0.39%, while the Shenzhen Component Index closed at 13289.0, down 1.03% [1] Company Performance - Weikang Pharmaceutical (300878) closed at 29.30, up 12.69% with a trading volume of 93,800 shares and a transaction value of 260 million [1] - Te Yi Pharmaceutical (002728) closed at 12.76, up 10.00% with a trading volume of 869,700 shares and a transaction value of 1.056 billion [1] - Tai Long Pharmaceutical (600222) closed at 7.51, up 9.96% with a trading volume of 630,600 shares and a transaction value of 461 million [1] - Yi Ling Pharmaceutical (002603) closed at 20.47, up 6.61% with a trading volume of 1,882,100 shares and a transaction value of 1.758 billion [1] - Zhongsheng Pharmaceutical (002317) closed at 21.25, up 4.17% with a trading volume of 893,600 shares and a transaction value of 1.854 billion [1] Market Dynamics - The traditional Chinese medicine sector saw a net inflow of 178 million from institutional investors, while retail investors experienced a net outflow of 1.3583 million [2] - The main capital flow for Te Yi Pharmaceutical showed a net inflow of 225 million, while retail investors had a net outflow of 127 million [3] - Tai Long Pharmaceutical had a net inflow of 83.56 million from main capital, with retail investors seeing a net outflow of 472.73 million [3]